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NCT06685250: CPOP
Postoperative Pain After a Laparoscopic Cholecystectomy
NA trial testing Laparoscopic cholecystectomy in Postoperative Pain in 190 participants. Not yet recruiting.
2 November 2025
Quick facts
| Lead sponsor | Hopital Charles Nicolle |
|---|---|
| Phase | NA |
| Status | Not yet recruiting |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | double |
| Primary purpose | other |
| Enrollment | 190 |
| Start date | 12 November 2024 |
| Primary completion | 2 November 2025 |
| Estimated completion | 2 December 2025 |
Drugs / interventions tested
- Laparoscopic cholecystectomy
Conditions studied
- Postoperative Pain — all drugs for Postoperative Pain →
Sponsor
Hopital Charles Nicolle — full company profile →
Who can join
18 and older, any sex, with Postoperative Pain. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Randomized Controlled Trial to compare the effect of low (8 mmHg) versus Standard (14 mmHg) insufflation pressure of CO2 pneumoperitoneum on postoperative pain in patients undergoing laparoscopic cholecystectomy
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Randomized controlled trial comparing low pressure (8 mmHg) versus high pressure (14 mmHg) CO2 insufflation on postoperative pain in patients undergoing laparoscopic cholecystectomy: Protocol.
Ben Safta A, Nasri S, Samaali I, Taher H, et al · · 2025 · PMID 41411326 · DOI 10.1371/journal.pone.0339161
Verify or expand the search:
- PubMed search for NCT06685250
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Laparoscopic cholecystectomy
Trials testing the same drug.
- NCT07001423 — ChOlecystectomy aFter successFul Endoscopic Common Bile Duct Stone Extraction in Elderly · NA · recruiting
- NCT07119203 — Surgical Techniques: Robotic Versus Conventional Laparoscopic Cholecystectomy IN Benign Gallbladder Disease · NA · recruiting
- NCT07161960 — Early Versus Delayed Cholecystectomy After Percutaneous Cholecystostomy in Moderate and Severe Cholecystitis (ESCAPE) · NA · recruiting
- NCT06459323 — the Outcomes of Laparoscopic Cholecystectomy for Acute Cholecystitis Within and Beyond the First 72 Hours, Does it Diffe · NA · not yet recruiting
- NCT06244589 — Evaluation of Risk Factors Leading to Conversion From Laparoscopic Cholecystectomy to Open Surgery · NA · completed
Other recruiting trials for Postoperative Pain
Currently open trials in the same condition.
- NCT07452120 — DIPB vs. SIFIB for Postoperative Analgesia After Hip Surgery · NA · recruiting
- NCT07396688 — Comparative Evaluation of the Effects of Calcium Hydroxide and BIO-C Temp Medicaments on Postoperative Pain in Patients · NA · recruiting
- NCT07413055 — Comparative Efficacy Of 4 mg VS. 8 mg Submucosal Dexamethasone In Postoperative Pain Management After Dental Implant Sur · Phase 3 · recruiting
- NCT07496086 — External Oblique Intercostal Block Versus Transversus Abdominis Plane Combined With Rectus Sheath Block on Postoperative · NA · recruiting
- NCT07396545 — External Oblique Intercostal Block Versus Erector Spinae Plane Block on Postoperative Pain in Laparoscopic Radical Gastr · NA · recruiting
Other Hopital Charles Nicolle trials
Trials by the same sponsor.
- NCT06881966 — The Effect of Omega-3 Fatty Acids in Patients With Rheumatoid Arthritis · NA · not yet recruiting
- NCT07094178 — Corticosteroid Versus PRP Injections for Shoulder Tendinopathy · NA · recruiting
- NCT07259655 — Management of Post-Induction Hypotension in Emergency Abdominal Surgery · Phase 4 · terminated
- NCT07289945 — Effects of Sevoflurane vs Desflurane on Early Recovery and Cognitive Function in Elderly Patients Undergoing Scheduled N · Phase 3 · completed
- NCT07358624 — Patient Satisfaction and Postoperative Pain After Diagnostic Hysteroscopy: Spinal Versus General Anesthesia · NA · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06685250 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Hopital Charles Nicolle
- Last refreshed: 12 November 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06685250.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing