Last reviewed · How we verify
NCT05543941: XPERIENCE
Evaluating XPERIENCE™ Advanced Surgical Irrigation
NA trial testing XPERIENCE Advanced Surgical Irrigation in Hip Osteoarthritis in 7,600 participants. Currently enrolling.
31 March 2027
Quick facts
| Lead sponsor | Ottawa Hospital Research Institute |
|---|---|
| Phase | NA |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | treatment |
| Enrollment | 7,600 |
| Start date | 1 April 2023 |
| Primary completion | 31 March 2027 |
| Estimated completion | 31 December 2027 |
| Sites | 9 locations across Canada |
Drugs / interventions tested
- XPERIENCE Advanced Surgical Irrigation
- Dilute Betadine
Conditions studied
- Hip Osteoarthritis — all drugs for Hip Osteoarthritis →
- Hip Arthritis — all drugs for Hip Arthritis →
- Knee Osteoarthritis — all drugs for Knee Osteoarthritis →
- Knee Arthritis — all drugs for Knee Arthritis →
Sponsor
Ottawa Hospital Research Institute
Who can join
18 and older, any sex, with Hip Osteoarthritis or Hip Arthritis. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
A prospective, multi-center, double-arm, parallel, interventional, randomized, controlled clinical trial to assess the rate of periprosthetic joint infection (PJI) in patients undergoing primary total knee arthroplasty (TKA), total hip arthroplasty (THA) or hip resurfacing (HR) with XPERIENCE™ (XP) Advanced Surgical Irrigation versus dilute Betadine (DB).
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Advances in Orthopedic Surgery Irrigation: A Review of Traditional Agents and the Emergence of Citrate-Based Solutions.
Ng MK, Razi AE. · · 2025 · cited 2× · PMID 40507443 · DOI 10.3390/jcm14113681
Verify or expand the search:
- PubMed search for NCT05543941
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Hip Osteoarthritis
Currently open trials in the same condition.
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Other Ottawa Hospital Research Institute trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05543941 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Ottawa Hospital Research Institute
- Last refreshed: 13 August 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05543941.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing