Last reviewed · How we verify
NCT05527171
Virtual Reality Mindfulness Meditation After ACL Reconstruction
NA trial testing Virtual Reality Mindfulness Meditation in Anterior Cruciate Ligament Injury in 48 participants. Currently enrolling.
30 June 2026
Quick facts
| Lead sponsor | University of North Carolina, Chapel Hill |
|---|---|
| Phase | NA |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | double |
| Primary purpose | treatment |
| Enrollment | 48 |
| Start date | 5 September 2023 |
| Primary completion | 30 June 2026 |
| Estimated completion | 30 June 2026 |
| Sites | 1 location across United States |
Drugs / interventions tested
- Virtual Reality Mindfulness Meditation
- Virtual Reality Sham
Conditions studied
- Anterior Cruciate Ligament Injury — all drugs for Anterior Cruciate Ligament Injury →
Sponsor
University of North Carolina, Chapel Hill
Who can join
Adults 14 to 25, female only, with Anterior Cruciate Ligament Injury. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
To evaluate the effect of virtual reality mindfulness meditation on patients after ACLR, the investigators will determine the effect of virtual reality mindfulness meditation to 1) decrease self-reported injury-related fear, 2) improve poor jump-landing movement patterns, and 3) improve brain activity in women 1 to 5 years post-ACLR when compared to a virtual reality sham group.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Virtual Reality Mindfulness Meditation for Patients After Anterior Cruciate Ligament Reconstruction: Protocol for the Development of a National Institutes of Health Stage 1 Behavioral Intervention.
Baez S, Marmura H, Pietrosimone B, Moser J. · · 2026 · PMID 42184365 · DOI 10.2196/91897
Verify or expand the search:
- PubMed search for NCT05527171
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Anterior Cruciate Ligament Injury
Currently open trials in the same condition.
- NCT06357091 — ACL Reconstruction With Shark Screw® or Biocomposite-interference Screws · NA · recruiting
- NCT03935750 — STABILITY 2: Anterior Cruciate Ligament Reconstruction +/- Lateral Tenodesis With Patellar vs Quad Tendon · NA · active not recruiting
- NCT03348995 — The BEAR III Trial for Bridge-Enhanced ACL (Anterior Cruciate Ligament) Restoration · NA · active not recruiting
Other University of North Carolina, Chapel Hill trials
Trials by the same sponsor.
- NCT06841913 — Woodsmoke Exposure, Influenza Infection, and Nasal Immunity · Phase 4 · suspended
- NCT07383428 — The INICIO-Guatemala Study · NA · not yet recruiting
- NCT07528443 — Ultraprocessed Foods in Colombia · NA · not yet recruiting
- NCT07507370 — CARED : A Novel Rapid Treatment Paradigm for Depression · NA · not yet recruiting
- NCT07534254 — Piloting a Generative Artificial Intelligence Chatbot in a Mobile Weight Loss Program · NA · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05527171 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University of North Carolina, Chapel Hill
- Last refreshed: 16 April 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05527171.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing