NCT05522049

Videolaryngoscopic Intubation Using Macintosh vs.Hyperangulated Blades in Patients With Expected Difficult Intubation

Completed NA Last updated 26 September 2023

What this trial tests

NA trial testing hyperangulated videolaryngoscope in Intubation; Difficult or Failed in 182 participants. Completed in 31 July 2023.

Timeline

17 October 2022

Primary endpoint
31 July 2023

31 July 2023

Quick facts

Lead sponsor	Universitätsklinikum Hamburg-Eppendorf
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	single
Primary purpose	other
Enrollment	182
Start date	17 October 2022
Primary completion	31 July 2023
Estimated completion	31 July 2023
Sites	1 location across Germany

Drugs / interventions tested

• hyperangulated videolaryngoscope
• Macintosh videolaryngoscope

Conditions studied

• Intubation; Difficult or Failed — all drugs for Intubation; Difficult or Failed →
• Videolaryngoscopy — all drugs for Videolaryngoscopy →
• General Anesthesia — all drugs for General Anesthesia →

Sponsor

Universitätsklinikum Hamburg-Eppendorf — full company profile →

Who can join

18 and older, any sex, with Intubation; Difficult or Failed or Videolaryngoscopy. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Videolaryngoscopy-guided intubation has become widespread as a means of preventing major complications relating to airway management by improving the glottic view, increasing the first attempt success rate, likely reduce rates of hypoxemic events, while reducing the rate of airway trauma. However, as randomized controlled studies in patients with anticipated difficult intubation undergoing ear nose and throat (ENT) or oral and maxillofacial (OMF) surgery are lacking, it is still unknown if hyperangulated blades improve glottic view and if their use translates into faster intubation. The primary aim of this randomized controlled trial is to compare the percentage of glottic opening (POGO) between hyperangulated blades and Macintosh blades in patients with expected difficult intubation undergoing ENT or OMF surgery who require transoral tracheal intubation. Secondary aims are to compare secondary outcome measures such as time variables, indicators for difficult and successful intubation, number of attempts, view conditions, difficult airway classifications and adverse events between both blade types.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

1. Classification of difficult videolaryngoscopic tracheal intubation with different blade types: a prospective external validation study of the VIDIAC score.
   Köhl V, Wünsch VA, Dohrmann T, Krause L, et al · · 2025 · cited 3× · PMID 40583245 · DOI 10.1111/anae.16678