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NCT05519345
Operant Conditioning After ACL Reconstruction
NA trial testing Operant Conditioning in Anterior Cruciate Ligament Injuries in 22 participants. Completed in 10 October 2023.
10 October 2023
Quick facts
| Lead sponsor | University of Michigan |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 22 |
| Start date | 28 December 2022 |
| Primary completion | 10 October 2023 |
| Estimated completion | 10 October 2023 |
| Sites | 1 location across United States |
Drugs / interventions tested
- Operant Conditioning
- Control
Conditions studied
- Anterior Cruciate Ligament Injuries — all drugs for Anterior Cruciate Ligament Injuries →
Sponsor
University of Michigan
Who can join
Adults 14 to 45, any sex, with Anterior Cruciate Ligament Injuries. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The purpose of this study is to examine if the changes in corticospinal function that accompany ACL reconstruction can be improved through a form of mental coaching and encouragement, known as operant conditioning.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Operant Upconditioning of the Quadriceps Motor Evoked Torque as a Means to Improve Quadriceps Function After ACL Reconstruction.
Rodriguez KM, Palmieri-Smith RM, Krishnan C. · · 2025 · PMID 39930348 · DOI 10.1177/19417381251313775
Verify or expand the search:
- PubMed search for NCT05519345
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Operant Conditioning
Trials testing the same drug.
- NCT04286191 — Physiological Changes Induced Through MEP Conditioning in People With SCI · NA · completed
- NCT03209531 — Conditioning Brain Responses to Improve Thigh Muscle Function After Anterior Cruciate Ligament Reconstruction · NA · completed
Other recruiting trials for Anterior Cruciate Ligament Injuries
Currently open trials in the same condition.
- NCT07501013 — Clinical Outcomes of Arthroscopic Surgeries for Shoulder and Knee Sports Injuries · recruiting
- NCT07333092 — Investigation of the Effects of Proprioceptive Exercises After Anterior Cruciate Ligament Surgery · NA · recruiting
- NCT07346326 — Comparative Study of Functional Outcomes Between Peroneus Longus and Hamstring Tendon Autografts in Arthroscopic ACL Rec · NA · recruiting
- NCT07306221 — Effect of Visual-Guided Balance Training on Knee Motor Function and Biomechanical Characteristics After ACL Reconstructi · NA · recruiting
- NCT07486466 — ACL Mechanical Property Changes in Female Collegiate Basketball Players During a Competitive Season · active not recruiting
Other University of Michigan trials
Trials by the same sponsor.
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- NCT07471646 — Effects of Ramadan Fasting With Exercise on Cardiometabolic Health · NA · not yet recruiting
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05519345 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University of Michigan
- Last refreshed: 23 January 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05519345.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing