NCT05513157

Investigation of Knee Hyperextension and Femoral Cartilage Thickness in Chronic Stroke Patients

Completed Last updated 13 June 2023

What this trial tests

trial in Stroke in 40 participants. Completed in 1 February 2023.

Timeline

15 August 2022

Primary endpoint
20 January 2023

1 February 2023

Quick facts

Lead sponsor	Hacettepe University
Status	Completed
Study type	OBSERVATIONAL
Enrollment	40
Start date	15 August 2022
Primary completion	20 January 2023
Estimated completion	1 February 2023
Sites	1 location across Turkey (Türkiye)

Conditions studied

• Stroke — all drugs for Stroke →

Sponsor

Hacettepe University

Who can join

Adults 40 to 65, any sex, with Stroke. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

It is aimed to measure knee hyperextension and knee joint cartilage thickness in chronic stroke patients and to examine the relationship between the factors affecting knee hyperextension and knee joint cartilage thickness.

This study, it is aimed to compare the knee joint cartilage thicknesses of the affected and unaffected extremities and to examine the relationship between knee hyperextension and knee joint cartilage thickness.

The second aim is to compare the knee joint cartilage thickness of the paretic and nonparetic extremities and in stroke patients with and without knee hyperextension.

The hypotheses of the study are:

Hypothesis 1;

H0: There is no difference between the knee joint cartilage thickness of the affected and unaffected extremities in chronic stroke patients with knee hyperextension.

H1: In chronic stroke patients with knee hyperextension, there is a difference between the knee joint cartilage thicknesses of the affected and unaffected extremities.

Hypothesis 2;

H0: There is no relationship between knee hyperextension during the stance phase of gait and knee joint cartilage thickness in chronic stroke patients.

H1: There is a relationship between knee hyperextension during the stance phase of gait and knee joint cartilage thickness in chronic stroke patients.

Hypothesis 3;

H0: There is no relationship between lower extremity muscle strength and spasticity and knee joint cartilage thickness in chronic stroke patients with knee hyperextension.

H1: There is a relationship between lower extremity muscle strength and spasticity and knee joint cartilage thickness in chronic stroke patients with knee hyperextension.

Hypothesis 4;

H0: There is no difference between the cartilage thickness of the knee joint in chronic stroke patients with and without knee hyperextension.

H1: There is a difference between the cartilage thickness of the knee joint in chronic stroke patients with and without knee hyperextension.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

1. Effect of Knee Hyperextension on Femoral Cartilage Thickness in Stroke Patients.
   Korkusuz S, Kibar S, Özgören N, Arıtan S, et al · · 2024 · cited 2× · PMID 37549370 · DOI 10.1097/phm.0000000000002323