NCT05497492 is a NA clinical trial of propofol in Anesthesia, sponsored by Beijing Friendship Hospital.

Who is sponsoring NCT05497492?

NCT05497492 is sponsored by Beijing Friendship Hospital.

What drugs are being tested in NCT05497492?

Interventions in NCT05497492: propofol, propofol and sufentanil, propofol and esketamine, propofol and lidocaine.

What condition does NCT05497492 study?

NCT05497492 studies Anesthesia.

Is NCT05497492 still recruiting?

NCT05497492 is currently status unknown. Last updated 10 October 2023.

Last reviewed 2023-10-10 · How we verify

NCT05497492

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Comparison of the Effects of Esketamine, Sufentanil, or Lidocaine on Tussis Reflection During Upper Gastroscopy

Status unknown NA Last updated 10 October 2023

What this trial tests

NA trial testing propofol in Anesthesia in 400 participants. Status unknown.

Timeline

5 November 2022

Primary endpoint
30 December 2023

30 December 2023

Quick facts

Lead sponsor	Beijing Friendship Hospital
Phase	NA
Status	Status unknown
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	triple
Primary purpose	prevention
Enrollment	400
Start date	5 November 2022
Primary completion	30 December 2023
Estimated completion	30 December 2023
Sites	1 location across China

Drugs / interventions tested

propofol (Propofol) — full drug profile →
propofol and sufentanil — full drug profile →
propofol and esketamine — full drug profile →
propofol and lidocaine — full drug profile →

Conditions studied

Anesthesia — all drugs for Anesthesia →

Sponsor

Beijing Friendship Hospital

Who can join

Adults 18 to 99, any sex, with Anesthesia. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

the frequency of tussis, nausea and vomiting, and/or body movements observed at the insertion of the endoscope into the pharyngeal cavity or within 5 min of endoscope insertion.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

Comparison of the effects of esketamine, sufentanil, or lidocaine combined with propofol on tussis reflection during upper gastrointestinal endoscopy: study protocol for a randomised, two centre, three-blind, controlled trial.
Hou HJ, Liu L, Tian M, Xue FS. · · 2024 · cited 1× · PMID 38178168 · DOI 10.1186/s13063-023-07812-0
Comparison of the effects of esketamine, sufentanil, or lidocaine combined with propofol on tussis reflection during upper gastrointestinal endoscopy: study protocol for a randomised, two centre, three-blind, controlled trial
Hou H, Liu L, Xue F, Tian M. · · 2022 · DOI 10.21203/rs.3.rs-1960083/v1

Verify or expand the search:

Other trials of propofol

Trials testing the same drug.

NCT07079176 — Etomidate Combined With Propofol Versus Propofol for Sedation in High-Altitude Patients During Gastroscopy: a Randomized · NA · not yet recruiting
NCT06907823 — Comparison of Sevoflurane and Propofol on ANI · NA · not yet recruiting
NCT06990763 — Network Pharmacology Was Applied to Explore the Mechanism of Remimazolam Applied in General Anesthesia for Gynecological · NA · not yet recruiting
NCT06976996 — Efficacy of Esketamine Combined With Different General Anesthetics on Quality of Postoperative Recovery · NA · active not recruiting
NCT07285980 — Comparison of Bier Block and Lidocaine-Propofol Mixture for Prevention of Propofol Injection Pain · NA · completed

Other recruiting trials for Anesthesia

Currently open trials in the same condition.

NCT07294092 — Ketamine and Propofol NeuroImaging · EARLY_PHASE1 · recruiting
NCT07290205 — Remimazolam NeuroImaging · EARLY_PHASE1 · recruiting
NCT07465185 — Intrathecal Bupivacaine With or Without Dexmetomidine for Cesserian Delivery · Phase 2 · recruiting
NCT07269808 — Sedation During Endoscopy Using Remimazolam: Efficacy in a Novel Exploration · Phase 3 · recruiting
NCT07443254 — Prospective IR-led Sedation Feasibility · Phase 1, PHASE2 · recruiting

Other Beijing Friendship Hospital trials

Trials by the same sponsor.

NCT07453862 — Novel Calcium Channel Modulators in RLS and Variants: Efficacy & Safety · Phase 1 · recruiting
NCT07397442 — Short-Course Radiotherapy Combined With Chemotherapy and Immunotherapy in Mid-Low Locally Advanced Rectal Cancer · Phase 2 · not yet recruiting
NCT07393048 — Application and Exploration of Personalized ctDNA-MRD Detection Technology in Predicting the Efficacy of Neoadjuvant The · recruiting
NCT07441850 — Digital Rehabilitation for Gastric Cancer Surgery After Neoadjuvant Therapy · NA · recruiting
NCT07369739 — Golidocitinib Combined With Selinexor for CAEBVD · Phase 2, PHASE3 · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT05497492 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Beijing Friendship Hospital
Last refreshed: 10 October 2023

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05497492.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing