NCT05494749

Zirconia Reinforced Glass Ionomer in MIH

Completed NA Last updated 19 March 2024

What this trial tests

NA trial testing zirconomer in Molar Incisor Hypomineralization in 88 participants. Completed in 30 December 2023.

Timeline

1 September 2022

Primary endpoint
30 December 2023

30 December 2023

Quick facts

Lead sponsor	Hams Hamed Abdelrahman
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	triple
Primary purpose	treatment
Enrollment	88
Start date	1 September 2022
Primary completion	30 December 2023
Estimated completion	30 December 2023
Sites	1 location across Egypt

Drugs / interventions tested

• zirconomer
• HVGI-Equia Forte

Conditions studied

• Molar Incisor Hypomineralization — all drugs for Molar Incisor Hypomineralization →

Sponsor

Hams Hamed Abdelrahman — full company profile →

Who can join

Adults 7 to 10, any sex, with Molar Incisor Hypomineralization. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Molar-incisor hypomineralization (MIH) is a qualitative enamel defect, in which molars and incisors involved are prone to post-eruptive enamel breakdown leading to sensitivity, and caries. Atraumatic/Alternative Restorative Treatment (ART) is a minimally invasive procedure. It can be very beneficial in managing MIH-affected molars in communities with limited access to dental care. Zirconia-reinforced GI was recently introduced. It is claimed to serve as a long-term temporary restoration until a more permanent restoration is placed

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

1. Zirconia-reinforced glass ionomer restorations in molar incisor hypomineralization: a randomized controlled clinical trial.
   Mahfouz RA, Hanno AG, Rahman AMAE. · · 2025 · PMID 40335753 · DOI 10.1007/s00784-025-06352-y