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NCT05494125
Effects of Continuous ESP Catheters on Recovery, Pain and Opioid Consumption After Multilevel Spine Surgery
NA trial testing Ropivacaine in Post Operative Pain in 10 participants. Terminated before completion.
31 December 2023
Quick facts
| Lead sponsor | Hospital for Special Surgery, New York |
|---|---|
| Phase | NA |
| Status | Terminated |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | double |
| Primary purpose | other |
| Enrollment | 10 |
| Start date | 14 September 2022 |
| Primary completion | 31 December 2023 |
| Estimated completion | 18 March 2024 |
| Sites | 1 location across United States |
Drugs / interventions tested
- Ropivacaine (ROPIVACAINE) — full drug profile →
- Placebo
Conditions studied
- Post Operative Pain — all drugs for Post Operative Pain →
- Spine Surgery — all drugs for Spine Surgery →
Sponsor
Hospital for Special Surgery, New York
Who can join
Adults 18 to 80, any sex, with Post Operative Pain or Spine Surgery. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Single-shot erector spinae plane (ESP) blocks (ESPB) are emerging as an intervention to improve pain and minimize opioid consumption after lumbar spine surgery. Although promising, there is minimal evidence to support routine use, and widespread clinical adoption may be limited to centers with advanced regional anesthesia resources and expertise. Continuous ESP catheter techniques may solve these problems but are associated with challenges of their own. This trial will investigate the role of adding surgeon-placed, continuous ESP catheters to single-shot ESPBs for patients undergoing multilevel spine surgery. It will assess whether adding ESP catheters with ropivacaine infusion for 48 hours after surgery offers opioid-minimizing analgesia and improves patient quality of recovery, compared to ESP catheters with saline/placebo infusion for 48 hours.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Continuous erector spinae plane catheters leading to unwanted neuraxial spread after spinal fusion surgery: a report of two cases from a terminated prospective randomized clinical trial.
Amoroso K, Hughes AP, Sama AA, Cammisa FP, et al · · 2023 · cited 5× · PMID 37192785 · DOI 10.1136/rapm-2023-104587
Verify or expand the search:
- PubMed search for NCT05494125
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Other recruiting trials for Post Operative Pain
Currently open trials in the same condition.
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- NCT07349810 — Post Operative Infusion Pump Pain Study · Phase 4 · recruiting
Other Hospital for Special Surgery, New York trials
Trials by the same sponsor.
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- NCT06180486 — Mindfulness Meditation Intervention Study · NA · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05494125 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Hospital for Special Surgery, New York
- Last refreshed: 23 April 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05494125.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing