NCT05491005 (eDIT) is a NA clinical trial of Total diet replacement in Diabetes Mellitus, Type 2, sponsored by Umeå University.

Who is sponsoring NCT05491005?

NCT05491005 is sponsored by Umeå University.

What drugs are being tested in NCT05491005?

Interventions in NCT05491005: Total diet replacement, eHealth, Face-to-face.

What condition does NCT05491005 study?

NCT05491005 studies Diabetes Mellitus, Type 2.

Is NCT05491005 still recruiting?

NCT05491005 is currently recruiting now. Last updated 1 July 2024.

Last reviewed 2024-07-01 · How we verify

NCT05491005: eDIT

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

The eHealth Diabetes Remission Trial

Recruiting now NA Last updated 1 July 2024

What this trial tests

NA trial testing Total diet replacement in Diabetes Mellitus, Type 2 in 106 participants. Currently enrolling.

Timeline

31 August 2022

Primary endpoint
31 December 2026

31 December 2026

Quick facts

Lead sponsor	Umeå University
Phase	NA
Status	Recruiting now
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	single
Primary purpose	treatment
Enrollment	106
Start date	31 August 2022
Primary completion	31 December 2026
Estimated completion	31 December 2026
Sites	3 locations across Sweden

Drugs / interventions tested

Total diet replacement
eHealth
Face-to-face

Conditions studied

Diabetes Mellitus, Type 2 — all drugs for Diabetes Mellitus, Type 2 →

Sponsor

Umeå University

Who can join

Adults 20 to 70, any sex, with Diabetes Mellitus, Type 2. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Overweight patients with type 2 diabetes are offered a total diet replacement with the goal of weight loss and diabetes remission. Study participants are randomised to eHealth follow-up or face-to-face follow-up, but the dietary advice is the same in both groups. A healthy control group with normal glucose tolerance is examined once but is not randomised and does not receive any intervention.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

Reduced antihypertensive treatment with maintained ambulatory blood pressure control following weight loss in type 2 diabetes.
Gladzki L, Brunström M, Otten J. · · 2026 · PMID 42154590 · DOI 10.1080/08037051.2026.2676362
eHealth versus face-to-face support for remission of type 2 diabetes by calorie restriction (eHealth DIabetes remission Trial): study protocol for a non-inferiority parallel group randomised controlled trial.
Otten J, Tellström A, Schien C, Chninou Y, et al · · 2025 · PMID 40701606 · DOI 10.1136/bmjopen-2024-095100

Verify or expand the search:

Other trials of Total diet replacement

Trials testing the same drug.

NCT05648903 — The Transform Type 2 Diabetes Study · NA · unknown

Other recruiting trials for Diabetes Mellitus, Type 2

Currently open trials in the same condition.

NCT07415954 — A Research Study Comparing How Well Different Doses of the Medicine NNC0662-0419 Lower Blood Sugar in People With Type 2 · Phase 2 · recruiting
NCT07532863 — A Real-world Study to Investigate Cardiovascular Risk Profile Among Newly Diagnosed Type 2 Diabetes Mellitus (T2DM) Part · recruiting
NCT07336329 — Continuous Glucose Monitoring in Non-Insulin Treated Type 2 Diabetes: Continuous vs. Periodic Use · NA · recruiting
NCT07242469 — A Clinical Trial of MK-1403 in Participants With Type 2 Diabetes Mellitus (MK-1403-006) · Phase 1 · recruiting
NCT07444203 — Transformative Research in Diabetic Nephropathy 2.0 · recruiting

Other Umeå University trials

Trials by the same sponsor.

NCT07407946 — Blended Trauma-Focused Cognitive Behavioral Therapy With Compassion · NA · recruiting
NCT07346820 — VDJ-recombination of the B-cell Receptor Following Hematopoietic Stem Cell Transplantation · not yet recruiting
NCT07417358 — Single-Stapled Technique for Colorectal Anastomosis · recruiting
NCT07316426 — Preoptimisation in Ventral Hernia Surgery · NA · recruiting
NCT07170722 — Sub-threshold DRG Stimulation vs Sham in Established Responders · NA · completed

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT05491005 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Umeå University
Last refreshed: 1 July 2024

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05491005.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing