NCT05483127 is a NA clinical trial of Verofilcon A toric soft contact lenses in Astigmatism, sponsored by Alcon Research.

Who is sponsoring NCT05483127?

NCT05483127 is sponsored by Alcon Research.

What drugs are being tested in NCT05483127?

Interventions in NCT05483127: Verofilcon A toric soft contact lenses, Stenfilcon A toric soft contact lenses.

What condition does NCT05483127 study?

NCT05483127 studies Astigmatism, Ametropia, Myopia.

Is NCT05483127 still recruiting?

NCT05483127 is currently completed. Last updated 2 November 2023.

Are results published for NCT05483127?

Yes — primary outcome results have been posted to ClinicalTrials.gov. See the outcomes section above for details.

Last reviewed 2023-11-02 · How we verify

NCT05483127

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Clinical Comparison of Two Daily Disposable Toric Soft Contact Lenses

Completed NA Results posted Last updated 2 November 2023

What this trial tests

NA trial testing Verofilcon A toric soft contact lenses in Astigmatism in 153 participants. Completed in 31 October 2022.

Timeline

13 September 2022

Primary endpoint
31 October 2022

31 October 2022

Quick facts

Lead sponsor	Alcon Research
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	crossover
Masking	double
Primary purpose	treatment
Enrollment	153
Start date	13 September 2022
Primary completion	31 October 2022
Estimated completion	31 October 2022
Sites	11 locations across United States

Drugs / interventions tested

Verofilcon A toric soft contact lenses
Stenfilcon A toric soft contact lenses

Conditions studied

Astigmatism — all drugs for Astigmatism →
Ametropia — all drugs for Ametropia →
Myopia — all drugs for Myopia →

Sponsor

Alcon Research — full company profile →

Who can join

18 and older, any sex, with Astigmatism or Ametropia. Patients with the condition only — healthy volunteers not accepted.

Results — posted to ClinicalTrials.gov

Per-arm endpoint measurements with 95% confidence intervals where reported. Source: trial results section.

Least Squares Means Distance Visual Acuity With Study Lenses at Week 1 Primary · Day 8 of each study lens type worn during the corresponding crossover period

Distance visual acuity (VA) was assessed with study lenses in place. VA was collected for each eye separately using logarithmic of the Minimum Angle of Resolution (logMAR) charts. LogMAR typically ranges from -0.3 (20/10 vision on the Snellen chart) to 1 (20/200 vision). A logMAR acuity of 0.0 corresponds to 20/20 Snellen (normal distance visual acuity), with a negative value denoting better than 20/20 visual acuity.

Group	Value	95% CI
PRECISION1 for Astigmatism (P1fA)	-0.11	± 0.005
MyDay Toric (MDT)	-0.10	± 0.005

Sponsor's own description

The primary purpose of this study is to demonstrate noninferiority in the visual acuity at distance when wearing PRECISION1™ for Astigmatism (P1fA) soft contact lenses compared to another commercially available, soft toric contact lens, MyDay® toric (MDT).

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.

Verify or expand the search:

Other trials of Verofilcon A toric soft contact lenses

Trials testing the same drug.

NCT06462456 — Post-market Clinical Follow-up Study of Alcon PRECISION1™ Spherical and PRECISION1™ for Astigmatism Soft Contact Lenses · terminated

Other recruiting trials for Astigmatism

Currently open trials in the same condition.

NCT07303920 — Wear Experience With Daily Disposable Contact Lenses for Astigmatism Over a Long-Wear Day · NA · recruiting
NCT07284966 — Comfort and Vision With TOTAL30 Multifocal Lenses · recruiting
NCT07078799 — Wavefront-guided LASIK Surgery Compared to Ray Tracing-Guided LASIK Surgery · NA · recruiting
NCT07084844 — Patient Reported Outcomes With WaveLight Plus LASIK · recruiting
NCT07140653 — Arcuate Incisions With Light Adjustable Lens for Astigmatism Correction in Lens Surgery · Phase 4 · recruiting

Other Alcon Research trials

Trials by the same sponsor.

NCT06884202 — Evaluation of Delefilcon A Contact Lenses · NA · completed
NCT06784063 — Visual Performance With Clareon® Vivity® Intraocular Lenses (IOLs) · NA · completed
NCT06571656 — Evaluation of the Safety and Tolerability of Ocular Lubricants · NA · terminated
NCT06660290 — A Study to Evaluate 0.003% AR-15512 Safety and Drop Attributes · Phase 3 · completed
NCT06483113 — DAILIES TOTAL1® Soft Contact Lenses - Post-Market Clinical Follow-up Study · terminated

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT05483127 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Alcon Research
Last refreshed: 2 November 2023

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05483127.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing