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NCT07140653
Arcuate Incisions With Light Adjustable Lens for Astigmatism Correction in Lens Surgery
Phase 4 trial testing Femto arcs in Astigmatism in 60 participants. Currently enrolling.
2 September 2026
Quick facts
| Lead sponsor | Center For Sight |
|---|---|
| Phase | Phase 4 |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | other |
| Enrollment | 60 |
| Start date | 2 September 2025 |
| Primary completion | 2 September 2026 |
| Estimated completion | 2 September 2026 |
| Sites | 2 locations across United States |
Drugs / interventions tested
- Femto arcs
- Light Adjustable Lens (LAL)
Conditions studied
- Astigmatism — all drugs for Astigmatism →
Sponsor
Center For Sight — full company profile →
Who can join
21 and older, any sex, with Astigmatism. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This study aims to evaluate the safety and effectiveness of femtosecond laser arcuate corneal relaxing incisions (AK) combined with Light Adjustable Lens (LAL) implantation for correcting pre-existing corneal astigmatism in patients undergoing cataract or refractive lens exchange surgery. Postoperative assessments will focus on residual refractive astigmatism, visual outcomes, patient satisfaction, and the incidence of adverse events. Arcuate keratotomy and toric IOLs are well-established methods for astigmatism correction, and this study will compare their combined effectiveness using advanced femtosecond laser technology.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT07140653
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Other Center For Sight trials
Trials by the same sponsor.
- NCT07277257 — Evaluating a New Therapy for Dry Eye in Patients With Sjögren's Syndrome · Phase 4 · recruiting
- NCT07260695 — Odyssey Evaluation in Post LASIK Patients · Phase 4 · recruiting
- NCT05604781 — Symfony/Synergy IOL Combination Outcomes · completed
- NCT05418153 — Synergy Lens Outcomes Evaluation · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07140653 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Center For Sight
- Last refreshed: 22 December 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07140653.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing