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NCT05475561
Comparison of Erector Spinae Block and Pecto-Intercostal Facial Block For Enhanced Recovery in Adult Cardiac Surgery
Phase 2 trial testing Ultrasound guided Pecto-intercostal- fascial plane block in Cardiac Septal Defects With Coarctation of the Aorta in 60 participants. Completed in 5 July 2022.
30 June 2022
Quick facts
| Lead sponsor | Alexandria University |
|---|---|
| Phase | Phase 2 |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | prevention |
| Enrollment | 60 |
| Start date | 25 May 2022 |
| Primary completion | 30 June 2022 |
| Estimated completion | 5 July 2022 |
| Sites | 1 location across Egypt |
Drugs / interventions tested
- Ultrasound guided Pecto-intercostal- fascial plane block
- Ultrasound guided erector spinae plane block — full drug profile →
- Bupivacain — full drug profile →
Conditions studied
- Cardiac Septal Defects With Coarctation of the Aorta — all drugs for Cardiac Septal Defects With Coarctation of the Aorta →
- Mitral Regurgitation — all drugs for Mitral Regurgitation →
Sponsor
Alexandria University
Who can join
Adults 18 to 50, any sex, with Cardiac Septal Defects With Coarctation of the Aorta or Mitral Regurgitation. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The current study is designed to compare the perioperative analgesic efficacy of Erector spinae plane block (ESPB) and Pecto-intercostal-fascial plane block (PIFB) in adults undergoing cardiac surgery via median sternotomy. The primary outcome measure will be the analgesic effectiveness of both blocks in median sternotomy pain, while the secondary outcome measures will be time to extubation, and length of intensive care unit stay.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
The molecular mechanisms of cardiac development and related diseases.
Li Y, Du J, Deng S, Liu B, et al · · 2024 · cited 53× · PMID 39715759 · DOI 10.1038/s41392-024-02069-8
Verify or expand the search:
- PubMed search for NCT05475561
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05475561 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Alexandria University
- Last refreshed: 27 July 2022
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05475561.
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