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Bupivacain
At a glance
| Generic name | Bupivacain |
|---|---|
| Also known as | Marcaine, Sensorcaine, IT mercaine, Bup, Marcain spinal tung., ATC-code: N01BB01 |
| Sponsor | Sisli Hamidiye Etfal Training and Research Hospital |
| Target | 5-hydroxytryptamine receptor 3A, Cytochrome P450 2D6, Potassium channel subfamily K member 3 |
| Modality | Small molecule |
| Therapeutic area | Ophthalmology |
| Phase | FDA-approved |
Approved indications
- Anesthesia for cesarean section
- Itching of skin
- Local Anesthesia for Ophthalmologic Procedure
- Local anesthesia
- Local anesthetic intrathecal block
- Major Nerve Block for Surgery
- Minor Skin Wound Pain
- Regional Anesthesia for Labor Pain
- Regional Anesthesia for Ophthalmologic Surgery
- Regional Anesthesia for Postoperative Pain
- Regional Anesthesia for Surgery
- Skin irritation
Common side effects
- Restlessness
- Anxiety
- Dizziness
- Tinnitus
- Blurred vision
- Tremors
- Drowsiness
- Nausea
- Vomiting
- Chills
- Headache
- Backache
Serious adverse events
- Convulsions
- Respiratory arrest
- Unconsciousness
- Total or High Spinal
- Cardiac arrest
- Respiratory paralysis
- Paralysis of lower extremities
- Septic meningitis
- Bradycardia
- Hypotension
Key clinical trials
- Continuous Epidural With Dexmedetomidine Adjuvant in Gynecologic Laparotomy (PHASE4)
- The Efficiency of Periarticular Multimodal Drug Injection in Pain Management Following Primary Unilateral TKA (NA)
- Sidekick vs Conventional Cannula in Lumbar Medial Branch Radiofrequency Ablation (NA)
- Efficacy of Modified Thoracoabdominal Nerves Block Through Perichondrial Approach in Total Laparoscopic Hysterectomies (NA)
- Comparison Of Clinical Outcomes of Intraperitoneal Bupivacaine Instillation Versus Placebo as Preemptive Analgesia in Patients Undergoing Open Appendectomy (PHASE1)
- Intraoperative Bupivacaine Injection to Reduce Acute and Chronic Pain After TVT/TVT-O Surgery. Randomized Double-Blind Trial (NA)
- Comparison of the Postoperative Analgesic Effects of SPSIPB and TPB in Mastectomy Operations (NA)
- Dexmedetomidine as an Adjuvant to Bupivacaine in Bilateral PECs for Pain Control After Cardiac Surgeries (PHASE4)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Bupivacain CI brief — competitive landscape report
- Bupivacain updates RSS · CI watch RSS
- Sisli Hamidiye Etfal Training and Research Hospital portfolio CI