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NCT05450679
Cervical Paraspinal Muscle Twitching and Cervical Facet Radiofrequency Ablation Outcomes
trial testing Cervical Radiofrequency Ablation (RFA) in Cervical Facet Joint Pain in 60 participants. Participants enrolled and being followed up; not accepting new ones.
1 August 2027
Quick facts
| Lead sponsor | Johns Hopkins University |
|---|---|
| Status | Active, enrolled |
| Study type | OBSERVATIONAL |
| Enrollment | 60 |
| Start date | 13 September 2022 |
| Primary completion | 1 August 2027 |
| Estimated completion | 1 August 2027 |
| Sites | 1 location across United States |
Drugs / interventions tested
- Cervical Radiofrequency Ablation (RFA)
Conditions studied
- Cervical Facet Joint Pain — all drugs for Cervical Facet Joint Pain →
- Chronic Pain — all drugs for Chronic Pain →
- Neck Pain — all drugs for Neck Pain →
Sponsor
Johns Hopkins University
Who can join
18 and older, any sex, with Cervical Facet Joint Pain or Chronic Pain. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The investigators aim to determine whether cervical paravertebral muscle twitching during motor testing as part of performing cervical RFAs is associated with a greater likelihood of treatment success, and greater magnitude or duration of analgesia. The investigators propose a straightforward grading scale based on visual and tactile information readily available during RFA procedures as part of routine practice (per radiofrequency electrode: 0 = no twitches palpated or observed; 1 = twitches palpated but not observed; 2 = twitches palpated and observed at 1-2 levels; 3= twitches palpated and observed at \>2 levels). If a higher weighted score (total score divided by number of radiofrequency lesion sites) correlates with a greater likelihood of treatment success, or magnitude or duration of analgesia following cervical RFA, cervical paraspinal muscle twitching may serve as a readily obtainable prognostic factor (marker) for effectiveness.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT05450679
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05450679 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Johns Hopkins University
- Last refreshed: 17 September 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05450679.
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