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NCT05448976
Potential Effect for the Smoking on Periodontitis From the Perspective of Arginine Metabolites
NA trial testing Saliva and serum sampling in Periodontitis in 80 participants. Completed in 16 May 2022.
6 April 2022
Quick facts
| Lead sponsor | Istanbul Medipol University Hospital |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | single group |
| Masking | none |
| Primary purpose | prevention |
| Enrollment | 80 |
| Start date | 12 August 2021 |
| Primary completion | 6 April 2022 |
| Estimated completion | 16 May 2022 |
| Sites | 1 location across Turkey (Türkiye) |
Drugs / interventions tested
- Saliva and serum sampling
Conditions studied
- Periodontitis — all drugs for Periodontitis →
- Smoking — all drugs for Smoking →
- Inflammatory Response — all drugs for Inflammatory Response →
Sponsor
Istanbul Medipol University Hospital
Who can join
Adults 18 to 65, any sex, with Periodontitis or Smoking. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Arginine metabolites are amino acids that are associated with vascular tone regulation and the level of inflammation, with critical roles in the synthesis of NO. Our aim was to determine the ADMA, SDMA, L-NMMA, L-arginine, L-homoarginine and IL-6 levels in saliva and serum samples from periodontitis patients and periodontally healthy individuals and to assess the levels of these compounds according to smoking status and compare these levels to those of healthy individuals.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT05448976
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Other recruiting trials for Periodontitis
Currently open trials in the same condition.
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Other Istanbul Medipol University Hospital trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05448976 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Istanbul Medipol University Hospital
- Last refreshed: 24 October 2023
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05448976.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing