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NCT05437471
Effects of Co-treatment on Endometrial abv3-integrin Expressions in Women With Recurrent Implantation Failure
NA trial testing GNRH Analoge, Duphaston, Letrozole in Miscarriage, Recurrent in 39 participants. Completed in 30 May 2022.
30 December 2021
Quick facts
| Lead sponsor | Universiti Kebangsaan Malaysia Medical Centre |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | supportive care |
| Enrollment | 39 |
| Start date | 1 January 2020 |
| Primary completion | 30 December 2021 |
| Estimated completion | 30 May 2022 |
| Sites | 1 location across Malaysia |
Drugs / interventions tested
- GNRH Analoge, Duphaston, Letrozole — full drug profile →
Conditions studied
- Miscarriage, Recurrent — all drugs for Miscarriage, Recurrent →
Sponsor
Universiti Kebangsaan Malaysia Medical Centre — full company profile →
Who can join
Adults 18 to 40, female only, with Miscarriage, Recurrent. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
To compare the abv3-integrin expression in endometrium tissue among RIF women between the GnRH analogue with Aromatase Inhibitor (Group A) , GnRH analogue with progesterone (Group B) and GnRH analogue alone as control group (Group C)
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT05437471
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Miscarriage, Recurrent
Currently open trials in the same condition.
- NCT05969574 — Is Decreased Ovarian Reserve Related to an Increased Number of Previous Early Miscarriages? · recruiting
- NCT04709796 — The Use of High Concentration Hyaluronic Acid (HA) Transfer Medium in Repeated Implantation Failure (RIF) Patients · NA · recruiting
- NCT06867900 — Unexplained Recurrent Pregnancy Loss: New Therapeutic Perspectives · NA · active not recruiting
Other Universiti Kebangsaan Malaysia Medical Centre trials
Trials by the same sponsor.
- NCT07466485 — The Efficacy of Tocotrienol Rich Fraction for Liver Protection in Adult Patients With Alcoholic Fatty Liver Disease (AFL · Phase 2 · recruiting
- NCT07041814 — A Study Comparing Different Treatment Approaches for the Initiation of Puberty in Girls With Turner Syndrome Using a TRI · Phase 2 · not yet recruiting
- NCT07000227 — Mechanism of FODMAP Restriction on FGID Patients · NA · recruiting
- NCT05694858 — Transdermal Microneedle Lignocaine Delivery Versus EMLA Patch for Topical Analgesia Before Venepuncture Procedure To Adu · Phase 1, PHASE2 · recruiting
- NCT07447310 — Comparing 360-degree VR Video of Local vs Overseas Environment on Psychological Health · NA · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05437471 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Universiti Kebangsaan Malaysia Medical Centre
- Last refreshed: 29 June 2022
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05437471.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing