Last reviewed · How we verify
NCT07000227: BRIDGE
Mechanism of FODMAP Restriction on FGID Patients
NA trial testing Low FODMAP diet in Functional Gastrointestinal Disorders (FGIDs) in 60 participants. Currently enrolling.
30 June 2026
Quick facts
| Lead sponsor | Universiti Kebangsaan Malaysia Medical Centre |
|---|---|
| Phase | NA |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 60 |
| Start date | 20 July 2025 |
| Primary completion | 30 June 2026 |
| Estimated completion | 30 September 2026 |
| Sites | 1 location across Malaysia |
Drugs / interventions tested
- Low FODMAP diet
- Gentle FODMAP diet
- Traditional Dietary Advice
Conditions studied
- Functional Gastrointestinal Disorders (FGIDs) — all drugs for Functional Gastrointestinal Disorders (FGIDs) →
- Irritable Bowel Syndrome (IBS) — all drugs for Irritable Bowel Syndrome (IBS) →
- Functional Dyspepsia — all drugs for Functional Dyspepsia →
Sponsor
Universiti Kebangsaan Malaysia Medical Centre — full company profile →
Who can join
18 and older, any sex, with Functional Gastrointestinal Disorders (FGIDs) or Irritable Bowel Syndrome (IBS). Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Brief Summary : The goal of this clinical trial is to investigate the effects of differing FODMAP diets on gut microbiota, gut barrier function, symptom severity, quality of life, and psychological status in FGID patients. The main question it aims to answer is : How does diets with differing FODMAP content affect the gut microbiota, gut barrier function, symptom severity, psychological status and quality of life in patients with FGID ? Researchers will compare low FODMAP diet, Gentle FODMAP diet and Traditional Dietary Advice (NICE guidelines) to see which diet is more suitable and effective for Malaysian FGID patients. Participants will : Be given either low FODMAP diet, Gentle FODMAP diet or Traditional Dietary Advice intervention and will be required to follow the intervention for two weeks. Be required to provide stool and blood samples during baseline and intervention Record 4 day food diary and complete assessing questionnaires during baseline and intervention
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT07000227
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Low FODMAP diet
Trials testing the same drug.
- NCT05326646 — Efficacy of a Low FODMAP Diet According to Colonic pH in Irritable Bowel Syndrome Patients · NA · terminated
- NCT05144204 — Evaluation of Treatment Effect of Low FODMAP Diet in Treatment of IBS Patients · NA · unknown
- NCT04841980 — Rifaximin Therapy vs Low FODMAP Diet In IBS · Phase 4 · unknown
- NCT05714189 — The Effect of Dietary Interventions, or no Intervention, on Pain and Quality of Life in Women Diagnosed With Endometrios · NA · completed
- NCT04054349 — The Effect of the Low Fodmap Diet in Children With Autism Spectrum Disorders · NA · completed
Other recruiting trials for Functional Gastrointestinal Disorders (FGIDs)
Currently open trials in the same condition.
- NCT06687057 — A Heart Rate Variability (HRV) Biofeedback Training in Functional Gastrointestinal Disorders (FGID) · NA · recruiting
Other Universiti Kebangsaan Malaysia Medical Centre trials
Trials by the same sponsor.
- NCT07466485 — The Efficacy of Tocotrienol Rich Fraction for Liver Protection in Adult Patients With Alcoholic Fatty Liver Disease (AFL · Phase 2 · recruiting
- NCT07041814 — A Study Comparing Different Treatment Approaches for the Initiation of Puberty in Girls With Turner Syndrome Using a TRI · Phase 2 · not yet recruiting
- NCT05694858 — Transdermal Microneedle Lignocaine Delivery Versus EMLA Patch for Topical Analgesia Before Venepuncture Procedure To Adu · Phase 1, PHASE2 · recruiting
- NCT07447310 — Comparing 360-degree VR Video of Local vs Overseas Environment on Psychological Health · NA · completed
- NCT06473077 — Effect of Placing the Endotracheal Tube Beyond Cervical C7 Level in Anterior Cervical Decompression and Fusion Surgery · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07000227 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Universiti Kebangsaan Malaysia Medical Centre
- Last refreshed: 12 August 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07000227.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing