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NCT05432024: ENABLE-CMR
Evaluation of Ablation Lesions Using Cardiovascular Magnetic Resonance Imaging
trial testing Catheter ablation in Atrial Fibrillation in 60 participants. Currently enrolling.
1 April 2028
Quick facts
| Lead sponsor | R&D Cardiologie |
|---|---|
| Status | Recruiting now |
| Study type | OBSERVATIONAL |
| Enrollment | 60 |
| Start date | 8 March 2023 |
| Primary completion | 1 April 2028 |
| Estimated completion | 1 April 2028 |
| Sites | 1 location across Netherlands |
Drugs / interventions tested
- Catheter ablation
Conditions studied
- Atrial Fibrillation — all drugs for Atrial Fibrillation →
Sponsor
R&D Cardiologie — full company profile →
Who can join
18 and older, any sex, with Atrial Fibrillation. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Ineffective ablation lesions can cause arrhythmia recurrence after catheter ablation for cardiac arrhythmia. Ablation lesions can be created with various ablation energy modalities. This study uses cardiovascular magnetic resonance imaging to evaluate the ablation lesion characteristics of radiofrequency ablation, ultra-low temperature cryo ablation, and pulsed field ablation. The ablation lesion characteristics of different energy characteristics will be compared. Additionally, arrhythmia recurrence and quality of life will be evaluated for the different energy modalities.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT05432024
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Catheter ablation
Trials testing the same drug.
- NCT07445334 — Catheter Ablation Versus Anti-arrhythmic Drugs for Premature Ventricular Complexes · NA · not yet recruiting
- NCT06632925 — Utility of Analyzing Atrial Signal Electrograms in Patients with Atrial Fibrillation Using Next-Generation Ensite X Soft · active not recruiting
- NCT06556485 — Preventive Catheter Ablation for Ventricular arrhythmiaS in Patients With End-sTage Heart faiLure · NA · recruiting
- NCT06560047 — Danish Evaluation of Early Catheter Ablation for Atrial Fibrillation in Patients With Heart Failure · NA · recruiting
- NCT06182566 — Hybrid Persistent Atrial Fibrillation Ablation in Heart Failure · NA · withdrawn
Other recruiting trials for Atrial Fibrillation
Currently open trials in the same condition.
- NCT07429214 — A Study of VARIPULSE Catheter and TRUPULSE Generator With VARIPULSE Pro Software in Participants With PAF or PsAF · NA · recruiting
- NCT07271238 — Feasibility Study on the VERAFEYE Imaging and Navigation System for Guided Catheter Ablation Procedures · NA · recruiting
- NCT07388108 — Atrial Dyssynchrony to Predict Arrhythmias in the Postoperative Setting of Cardiovascular Surgery. · recruiting
- NCT07428967 — AV Node Ablation and CONDUCTion System Pacing for Atrial Fibrillation With Preserved Left Ventricular Function · NA · recruiting
- NCT06650995 — AlEX-DHF: Ablation and Exercise in Diastolic Heart Failure · NA · recruiting
Other R&D Cardiologie trials
Trials by the same sponsor.
- NCT04676880 — Left Atrial Appendage Occlusion for AF Patients Unable to Use Oral Anticoagulation Therapy · NA · active not recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05432024 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by R&D Cardiologie
- Last refreshed: 28 July 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05432024.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing