Last reviewed · How we verify
NCT05425810: ENABLE
R21: An Easy-to-use, iNtelligent, Affordable LinEr (ENABLE) System for Socket Fit Assessment
NA trial testing Apply ENABLE sensing pad in Lower Limb Amputation Below Knee (Injury) in 3 participants. Currently enrolling.
30 January 2026
Quick facts
| Lead sponsor | North Carolina State University |
|---|---|
| Phase | NA |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | device feasibility |
| Enrollment | 3 |
| Start date | 20 April 2021 |
| Primary completion | 30 January 2026 |
| Estimated completion | 27 February 2026 |
| Sites | 1 location across United States |
Drugs / interventions tested
- Apply ENABLE sensing pad
- Insert small pads at pressure tolerant locations
Conditions studied
- Lower Limb Amputation Below Knee (Injury) — all drugs for Lower Limb Amputation Below Knee (Injury) →
Sponsor
North Carolina State University
Who can join
Adults 18 to 99, any sex, with Lower Limb Amputation Below Knee (Injury). Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Lower limb amputees (LLA) rely on their prosthetic legs to remain active and lead an independent life. For most LLAs, a well-fitted prosthetic socket is the only option to interface with their prosthetic leg, however, it is a real challenge to make a prosthetic socket to interface with residual limbs accurately. One of the reasons is that there lack of accurate approaches to evaluate the pressure distribution on the residual limb accurately and effectively. To overcome this issue, the research team will develop an innovative sensing system, which permits the prosthetists to track the pressure distribution on the residual limb visually. The capability of the new sensing system will be demonstrated on lower limb amputees.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT05425810
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Lower Limb Amputation Below Knee (Injury)
Currently open trials in the same condition.
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- NCT05471375 — C-STAR Movement Database · recruiting
- NCT05915065 — VR to Evaluate Phantom Limb Pain · NA · active not recruiting
- NCT04305782 — NIH Release/Relock Socket · NA · recruiting
Other North Carolina State University trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05425810 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by North Carolina State University
- Last refreshed: 20 May 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05425810.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing