Last reviewed · How we verify
NCT07206797
Ultrasound for Quantifying Muscle Activation Elicited by Spinal Cord Stimulation and Functional Electrical Stimulation
NA trial testing Functional Electrical Stimulation in Neuromodulatory Effects of TSCS and FES in Lower Limbs in 30 participants. Currently enrolling.
1 June 2026
Quick facts
| Lead sponsor | North Carolina State University |
|---|---|
| Phase | NA |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | other |
| Enrollment | 30 |
| Start date | 1 June 2025 |
| Primary completion | 1 June 2026 |
| Estimated completion | 1 June 2026 |
| Sites | 1 location across United States |
Drugs / interventions tested
- Functional Electrical Stimulation
- Transcutaneous (Non-Invasive) Spinal Cord Stimulation
- Ultrasound
Conditions studied
- Neuromodulatory Effects of TSCS and FES in Lower Limbs — all drugs for Neuromodulatory Effects of TSCS and FES in Lower Limbs →
Sponsor
North Carolina State University
Who can join
Adults 18 to 60, any sex, with Neuromodulatory Effects of TSCS and FES in Lower Limbs. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Transcutaneous (non-invasive) spinal cord stimulation (tSCS) has been shown to facilitate volitional motor activity in patients with spinal cord injury. tSCS is known to activate the same neural structures as invasive SCS, meaning it may have the potential for functional restoration without an expensive surgical implant. Functional electrical stimulation (FES) is also used in therapy for patients with spinal cord injury to locally activate paralyzed or weakened muscles. There is evidence that combining FES and tSCS may elicit greater muscle activation than either modality alone. The objective of this study is to quantify the torque at the ankle joint generated by tSCS, by FES, and by tSCS + FES. Additionally, ultrasound images will be collected during stimulation to provide a metric of muscle activity. The correlation between ultrasound and torque will be assessed to determine if ultrasound is a useful modality for quantifying tSCS-elicited muscle activity.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT07206797
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Functional Electrical Stimulation
Trials testing the same drug.
- NCT07492602 — Comparison of Gait Metrics in Patients With Stroke, Traumatic Brain Injury, and Multiple Sclerosis · NA · not yet recruiting
- NCT07506499 — Cardiac Rehabilitation in Decompensated Heart Failure · NA · recruiting
- NCT07130929 — Functional Electrical Stimulation to Treat Critical Neuromyopathy After Severe Stroke: a Pilot Study. · NA · recruiting
- NCT06953284 — Kinesiotaping Versus Functional Electrical Stimulation on Equinus Deformity · NA · enrolling by invitation
- NCT06912217 — Comparison of the Effects of Robotic Rehabilitation, Functional Electrical Stimulation and Occupational Therapy on Upper · NA · completed
Other North Carolina State University trials
Trials by the same sponsor.
- NCT07216183 — Epidermal Sensors for Wireless and Enhanced Amputee Skin Tracking (E-SWEAT) Part 1 · Phase 1 · recruiting
- NCT07218978 — Ripe for Revival: Outcomes Evaluation of a Mobile Produce Market With Vouchers · NA · recruiting
- NCT07204925 — Towards Efficient Personalization of Computerized Lower Limb Prostheses Via Reinforcement Learning in a Clinical Setup - · Phase 1 · recruiting
- NCT07489118 — Impact of Protein Source and Polyphenol Complexation in Protein Bars on Metabolic Health · NA · active not recruiting
- NCT07221045 — A Food As Medicine Approach to Address Food Insecurity in Rural North Carolina · NA · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07206797 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by North Carolina State University
- Last refreshed: 14 October 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07206797.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing