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NCT05425784
Home Use of Dual-light Photodynamic Therapy for Chronic Periodontitis
NA trial testing Lumoral treatment in Periodontal Diseases in 41 participants. Completed in 13 January 2025.
29 April 2024
Quick facts
| Lead sponsor | Koite Health Oy |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | triple |
| Primary purpose | treatment |
| Enrollment | 41 |
| Start date | 19 January 2023 |
| Primary completion | 29 April 2024 |
| Estimated completion | 13 January 2025 |
| Sites | 3 locations across Finland |
Drugs / interventions tested
- Lumoral treatment
- Standard oral hygiene self care
Conditions studied
- Periodontal Diseases — all drugs for Periodontal Diseases →
- Periodontitis — all drugs for Periodontitis →
- Plaque, Dental — all drugs for Plaque, Dental →
- Plaque Induced Gingivitis — all drugs for Plaque Induced Gingivitis →
Sponsor
Koite Health Oy — full company profile →
Who can join
Adults 18 to 85, any sex, with Periodontal Diseases or Periodontitis. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This early-stage research is designed to determine the efficacy of the Lumoral method in chronic periodontitis patients. Improved supragingival plaque control can help to also sustain the subgingival plaque management in the long term. In addition, the device might have a photobiomodulation effect on periodontal tissues.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
A multicenter, controlled, randomized trial of home-applied dual-light photodynamic therapy in stage I to III periodontitis (LumoNorth2022 study).
Tegelberg P, Ojala M, Ylipalosaari M, Lindroth J, et al · · 2026 · PMID 42117907 · DOI 10.1002/jper.70120
Verify or expand the search:
- PubMed search for NCT05425784
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Lumoral treatment
Trials testing the same drug.
- NCT05401201 — Dual-light Antibacterial Photodynamic Therapy as an Adjunctive Treatment to Corticosteroid Treatment in OLP · NA · completed
Other recruiting trials for Periodontal Diseases
Currently open trials in the same condition.
- NCT07358104 — Efficacy of Camel Whey Protein and Camel Whey Protein Nanoparticles for Treating Intra-bony Periodontal Defects · NA · active not recruiting
- NCT07312045 — HALP Score, Blood-Based Inflammatory Indices, and Salivary MMP-8 in Periodontal Disease and Healing After Non-Surgical T · recruiting
- NCT07384221 — Periodontal Status and Disease Severity in Pemphigus Vulgaris Patients · recruiting
- NCT07530978 — ORAL HYGIENE, PERIODONTAL STATUS AND QUALITY OF LIFE · recruiting
- NCT06848790 — Interdental Hygiene Methods in Young Adults · NA · recruiting
Other Koite Health Oy trials
Trials by the same sponsor.
- NCT06860321 — Photodynamic Treatment in the Management of Residual Biofilm - a Crossover Study · NA · completed
- NCT05825742 — Regular Home Use of Dual-light Photodynamic Therapy on Oral Health in Adolescents Undergoing Fixed Orthodontic Treatment · NA · completed
- NCT05698823 — Regular Home-use of Dual-light Photodynamic Therapy in the Management of Chronic Stage III-IV Periodontitis · NA · completed
- NCT05401201 — Dual-light Antibacterial Photodynamic Therapy as an Adjunctive Treatment to Corticosteroid Treatment in OLP · NA · completed
- NCT05361590 — Impact of Regular Home Use of Lumoral Dual-light Photodynamic Therapy on Plaque Control and Gingival Health · NA · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05425784 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Koite Health Oy
- Last refreshed: 18 February 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05425784.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing