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NCT05423847: TrUST
Triage UltraSound in Tb Endemic Regions
trial testing POCUS in Tuberculosis in 504 participants. Completed in 10 February 2025.
11 August 2023
Quick facts
| Lead sponsor | Centre Hospitalier Universitaire Vaudois |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 504 |
| Start date | 14 October 2021 |
| Primary completion | 11 August 2023 |
| Estimated completion | 10 February 2025 |
| Sites | 3 locations across South Africa, Mali, Benin |
Drugs / interventions tested
- POCUS
Conditions studied
- Tuberculosis — all drugs for Tuberculosis →
- Lower Resp Tract Infection — all drugs for Lower Resp Tract Infection →
- Pneumonia — all drugs for Pneumonia →
Sponsor
Centre Hospitalier Universitaire Vaudois
Who can join
18 and older, any sex, with Tuberculosis or Lower Resp Tract Infection. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
In Sub-Saharan Africa, lower respiratory tract infections (LRTIs) and tuberculosis (TB) jointly are the leading cause of overall mortality. There is a need to integrate sustainable triage and management strategies into standard care. The TrUST study investigates the utility of point-of-care ultrasound (POCUS) for diagnosis and prognosis of LRTIs in TB endemic regions in the outpatient triage setting. Automated interpretation of POCUS by artificial intelligence (AI) may further standardize and improve its predictive utility as well as facilitate its implementation into usual practice.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Barriers and facilitators to implementation of point-of-care lung ultrasonography in a tertiary centre in Benin: a qualitative study among general physicians and pneumologists.
Suttels V, Guedes Da Costa S, Garcia E, Brahier T, et al · · 2023 · cited 8× · PMID 37369423 · DOI 10.1136/bmjopen-2022-070765
Verify or expand the search:
- PubMed search for NCT05423847
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of POCUS
Trials testing the same drug.
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- NCT05880277 — Diagnostic POCUS of Patellar Tendinopathy in Female Athletes · NA · unknown
- NCT05602077 — Accuracy of Sonography in Elbow Trauma · NA · completed
- NCT07046793 — Fracture Ultrasound in Kids Wirst Trial (FRUSKI-Wrist) · completed
Other recruiting trials for Tuberculosis
Currently open trials in the same condition.
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- NCT06318416 — Precision Rifampin Trial for Personalized Dosing · Phase 1 · recruiting
- NCT07170800 — A Phase 2b Clinical Study of JDB0131 Benzenesulfonate Tablets · Phase 2 · recruiting
Other Centre Hospitalier Universitaire Vaudois trials
Trials by the same sponsor.
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- NCT07139756 — Deciphering the Mechanisms of Central BP Regulation in Patients With PD Associated With Orthostatic Hypotension · not yet recruiting
- NCT07109388 — Comparison of Pericapsular Nerve Group (PENG) Block With a Combined Femoral, Sciatic, Lateral Femoral Cutaneous Nerve Bl · NA · not yet recruiting
- NCT07268378 — Supervision of Clinicians in Oncology by Psycho-oncologists : Evaluation · NA · enrolling by invitation
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05423847 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Centre Hospitalier Universitaire Vaudois
- Last refreshed: 13 February 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05423847.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing