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NCT05405816
Determination of Change in Reflux Disease After Sleeve Gastrectomy by Intraluminal Impedance and pH-meter
NA trial testing laparoscopic sleeve gastrectomy in Gastroesophageal Reflux Disease in 20 participants. Completed in 1 September 2022.
1 August 2022
Quick facts
| Lead sponsor | Fatih Sultan Mehmet Training and Research Hospital |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | non randomized |
| Design | single group |
| Masking | double |
| Primary purpose | diagnostic |
| Enrollment | 20 |
| Start date | 1 January 2022 |
| Primary completion | 1 August 2022 |
| Estimated completion | 1 September 2022 |
| Sites | 1 location across Turkey (Türkiye) |
Drugs / interventions tested
- laparoscopic sleeve gastrectomy
Conditions studied
- Gastroesophageal Reflux Disease — all drugs for Gastroesophageal Reflux Disease →
- Obesity, Morbid — all drugs for Obesity, Morbid →
Sponsor
Fatih Sultan Mehmet Training and Research Hospital
Who can join
Adults 18 to 65, any sex, with Gastroesophageal Reflux Disease or Obesity, Morbid. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
710 / 5.000 Çeviri sonuçları Laparoscopic sleeve gastrectomy (LSG) has become the most common bariatric procedure in obesity. The overall relationship between sleeve gastrectomy and gastroesophageal reflux disease is still unclear. Only acid reflux can be detected in the esophagus with a standard 24-hour pH-meter. A 24-hour pH-meter is normal in 30-50% of patients with nonerosive reflux. Impedance-pH meter, on the other hand, is a newly developed technique and determines all kinds of reflux (gas, liquid, acid and non-acid), the level of reflux and the clearance time of the esophagus. This prospective series aims to examine the relationship between LSG operation and esophago-gastric physiology using intraluminal impedance testing before and after LSG operation.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Systematic mapping of registered interventional studies addressing the top 10 research priorities in Barrett's oesophagus and gastro-oesophageal reflux disease.
Gamakaranage C, Ratcliffe E, Britton J, Butler T, et al · · 2025 · PMID 40527525 · DOI 10.1136/bmjgast-2025-001738
Verify or expand the search:
- PubMed search for NCT05405816
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
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Trials testing the same drug.
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- NCT04652336 — Study Comparing the Effect of Ligamentum Teres Cardiopexy on de Novo GERD Post LSG · NA · unknown
- NCT04508634 — Treating Obese PCOS Patients With LSG vs. Met · Phase 4 · unknown
- NCT04554082 — Evaluation of Micronutrients in Obese Patients · completed
Other recruiting trials for Gastroesophageal Reflux Disease
Currently open trials in the same condition.
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- NCT06991348 — Clinical Trial for the Comparative Evaluation of Acid Suppression and Symptom Management of Gastroesophageal Reflux Dise · Phase 4 · recruiting
- NCT06732661 — Preserving the Pre-cardial Fat Pad During Sleeve Gastrectomy on Postoperative Gastroesophageal Reflux · NA · active not recruiting
- NCT05514769 — Proximal Gastrectomy Anterior Anastomosis With Pyloroplasty Versus Esophagogastric Anastomosis for Gastric Cancer · NA · recruiting
Other Fatih Sultan Mehmet Training and Research Hospital trials
Trials by the same sponsor.
- NCT07589582 — Active Noise-Cancelling Headphones Reduce Operative Time and Improve Procedural Consistency in ACL Reconstruction l · NA · active not recruiting
- NCT07523828 — Laryngeal Edema Assessment by Cuff Leak Test and Ultrasound in ICU Patients and Its Relationship With Weaning Success · not yet recruiting
- NCT07487038 — The Efficacy and Safety of a Single-Dose Hyaluronic Acid Injection in the Treatment of Knee Osteoarthritis · not yet recruiting
- NCT07485465 — Lymphoedema Diagnosis and Treatment · not yet recruiting
- NCT07451925 — Prediction of Postoperative Pain Using Venous Cannulation Pain and Preoperative Anxiety Scores · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05405816 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Fatih Sultan Mehmet Training and Research Hospital
- Last refreshed: 13 February 2023
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05405816.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing