Last reviewed · How we verify
Gastroesophageal reflux disease
Approved treatments
- Dexpure
Dexpure works by irreversibly inhibiting the H+/K+ ATPase enzyme in the stomach lining, reducing acid production. - Metaclopramide · Institute of Liver and Biliary Sciences, India
- Bss · B Braun
ANTICOAGULANT CITRATE DEXTROSE SOLUTION USP (ACD) SOLUTION A prevents blood clotting by binding free calcium, a crucial co-factor in the clotting cascade. - Gaviscon · Sanofi
- Renacidin · United Guardian
- Dexilant · Takeda
Dexlansoprazole inhibits gastric acid secretion by blocking the (H+, K+)-ATPase enzyme, known as the proton pump, in gastric parietal cells. - Milk of Magnesia · Generic (multiple manufacturers)
- Reglan · Hikma
- Reglan · Hikma
Metoclopramide stimulates upper GI tract motility by sensitizing tissues to acetylcholine action. - Noltec
- Zantac · GSK (originally Glaxo)
- Dexlan · Chang Gung Memorial Hospital
- Pepcid · Generic (originally Yamanouchi/Merck)
Competitively blocks histamine H2 receptors on gastric parietal cells, reducing basal and stimulated acid secretion. - Dexilant · Genuine Research Center, Egypt
- Gaviscon · Sanofi
- Prevacid · Vanderbilt University Medical Center
- Nexium · AstraZeneca
- Protonix · Generic (originally Byk Gulden/Altana/Nycomed)
Irreversibly inhibits the gastric proton pump (H+/K+ ATPase), suppressing stomach acid secretion. - aluminum carbonate
Aluminum carbonate works by neutralizing stomach acid and forming a protective barrier over the stomach lining. - carbaldrate
Carbaldrate works by reducing stomach acid production. - Gelusil
- Potassium Alum · Novartis Pharmaceuticals
- Pantoprazole Sodium · Pfizer
Pantoprazole suppresses gastric acid by covalently binding the (H+, K+)-ATPase enzyme at parietal cells. - Prilosec · AstraZeneca (originally Astra AB)
Irreversibly inhibits the hydrogen-potassium ATPase (proton pump) in gastric parietal cells, potently suppressing stomach acid secretion. - Aciphex · University of Utah
- Tagamet
- Aciphex · Waylis
Aciphex works by irreversibly inhibiting the potassium-transporting ATPase enzyme in the stomach lining, reducing acid production. - Alimix
- Axid Ar
- Rabeprazol · Janssen-Cilag, S.A.
- Omeprazol · RenJi Hospital
- Pantoprazol · Northern Orthopaedic Division, Denmark
- Prevacid · Generic (originally Takeda)
Irreversibly inhibits the gastric proton pump to suppress acid secretion.
Clinical guidelines
- FDA label — 1L
Omeprazole is used to treat gastroesophageal reflux disease (GERD). - FDA label — 2L
Treatment for 4 to 12 weeks of symptomatic, documented gastroesophageal reflux in adults who fail to respond to conventional therapy.
Competitive intelligence
For the full treatment-landscape CI brief — marketed leaders side-by-side, pipeline by phase, recent regulatory actions, sponsor landscape:
- Gastroesophageal reflux disease patent landscape — cliff calendar, originator estates, attackable patents
- Gastroesophageal reflux disease treatment landscape brief
- Gastroesophageal reflux disease treatment updates RSS
Frequently asked questions about Gastroesophageal reflux disease
What drugs treat Gastroesophageal reflux disease?
Tracked treatments include Dexpure, Metaclopramide, Bss, Gaviscon, Renacidin, Dexilant, Milk of Magnesia, Reglan.
What is the treatment for Gastroesophageal reflux disease?
Standard treatment for Gastroesophageal reflux disease includes Dexpure, Metaclopramide, Bss, Gaviscon, Renacidin. See the treatment landscape page for first-line, second-line and salvage options.
What are the treatment guidelines for Gastroesophageal reflux disease?
FDA label publishes guidelines for Gastroesophageal reflux disease. 2 guideline references tracked.
Related
- Treatment landscape: Gastroesophageal reflux disease patent cliff · Gastroesophageal reflux disease CI report
- Treatment: Dexpure
- Treatment: Metaclopramide · Institute of Liver and Biliary Sciences, India
- Treatment: Bss · B Braun
- Treatment: Gaviscon · Sanofi
- Treatment: Renacidin · United Guardian
- All diseases: Browse the disease index · Disease landscape hub
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing