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NCT05403840: STRESS-MR
Haemodynamics of Mitral Regurgitation Reduction
trial testing Mitral valve surgery in Mitral Regurgitation in 60 participants. Status unknown.
6 June 2024
Quick facts
| Lead sponsor | Guy's and St Thomas' NHS Foundation Trust |
|---|---|
| Status | Status unknown |
| Study type | OBSERVATIONAL |
| Enrollment | 60 |
| Start date | 6 June 2022 |
| Primary completion | 6 June 2024 |
| Estimated completion | 6 January 2025 |
Drugs / interventions tested
- Mitral valve surgery
- Transcatheter mitral valve intervention
Conditions studied
- Mitral Regurgitation — all drugs for Mitral Regurgitation →
Sponsor
Guy's and St Thomas' NHS Foundation Trust
Who can join
18 and older, any sex, with Mitral Regurgitation. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
There is uncertainty in terms of the superiority of conventional valve surgery or percutaneous transcatheter intervention for the treatment of severe mitral regurgitation (MR) in high risk patients. The post procedural haemodynamics of the different treatment options in those at high surgical risk is poorly understood. This study seeks to characterise the physiological changes and functional outcomes of patients undergoing either surgery or transcatheter intervention.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT05403840
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Mitral valve surgery
Trials testing the same drug.
- NCT06255457 — Ventricular Arrhythmias in Patients Undergoing Mitral Valve Surgery · recruiting
- NCT05774795 — LOng-Term Fate of Moderate Aortic Regurgitation Left Untreated at the Time of Mitral Valve Surgery · completed
- NCT04813692 — Mechanical Complications of Acute Myocardial Infarction During COVID-19 Pandemics · completed
Other recruiting trials for Mitral Regurgitation
Currently open trials in the same condition.
- NCT07450911 — A Clinical Study Evaluating the Replacement of the Native Mitral Valve Using the ReValve System · Phase 1 · recruiting
- NCT07366723 — The Role of cardIac magNeTic rEsonance in surGical Decision Making in Patients With Severe pRimAry miTral rEgurgitation · NA · active not recruiting
- NCT07007143 — STrategies for Antithrombotic tReatment Following Transcatheter Edge-to-Edge Repair in Patients Without an Indication fo · Phase 4 · recruiting
- NCT07108907 — Outcome Registry and Assessment of New Edge-to-Edge Repair · recruiting
- NCT06901466 — STrategies for Antithrombotic tReatment Following Transcatheter Edge-to-Edge Repair in Patients With an Indication for O · Phase 4 · recruiting
Other Guy's and St Thomas' NHS Foundation Trust trials
Trials by the same sponsor.
- NCT07534917 — Comparing the Effects of Newer Pacemakers and Their Effects on the Heart and Valve Function in the Short-term. · not yet recruiting
- NCT07454135 — Mechanisms of Atrial Pathoelectrophysiology in HCM · not yet recruiting
- NCT07419945 — Older Kidney Patient Optimisation Pretransplant · NA · not yet recruiting
- NCT07309835 — Improving Genetic Medicine for Ethnic Minority Groups · not yet recruiting
- NCT07203872 — Inflammation-resolution Therapy in MINST of Periodontal Intrabony Defect: a Pilot Randomised Controlled Trial · NA · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05403840 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Guy's and St Thomas' NHS Foundation Trust
- Last refreshed: 3 June 2022
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05403840.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing