NCT05402683

Ultrasound Versus Clinical Tests as Predictors of Difficult Endotracheal Intubation in Patients With Obstructive Sleep Apnoea Undergoing Elective Surgery Under General Anaesthesia

Status unknown Last updated 2 June 2022

What this trial tests

trial in Difficult Intubation in Obstructive Sleep Apnea in 70 participants. Status unknown.

Timeline

1 February 2022

Primary endpoint
31 January 2023

31 January 2023

Quick facts

Lead sponsor	Tanta University
Status	Status unknown
Study type	OBSERVATIONAL
Enrollment	70
Start date	1 February 2022
Primary completion	31 January 2023
Estimated completion	31 January 2023
Sites	1 location across Egypt

Conditions studied

• Difficult Intubation in Obstructive Sleep Apnea — all drugs for Difficult Intubation in Obstructive Sleep Apnea →

Sponsor

Tanta University

Who can join

Adults 21 to 60, any sex, with Difficult Intubation in Obstructive Sleep Apnea. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Obstructive sleep apnoea (OSA) is the most serious kind of the sleep-disordered breathing group, characterised by recurrent episodes of partial to complete obstruction of the upper airway resulting in inefficient alveolar gas exchange and desaturation\[1\].

It is a commonly encountered condition with a reported prevalence of 9-25% in the general population \[2\].

However, the majority of OSA patients presenting for surgery remain undiagnosed or untreated\[3\], contributing to a high rate of unexpected adverse airway outcome\[4\].

The various airway abnormalities represented by OSA include a large tongue, collapsible airway and crowding of the oropharyngeal structures, among others\[5\].

Accurate airway assessment should always be performed so as to provide appropriate planning and management of expected difficult intubation, but the common clinical screening tests (Mallampati score, inter-incisor distance, mento-hyoid distance, BMI, etc ) have shown low sensitivity and specificity with a limited predictive value, especially if only a single assessment method is used\[6\].

Ultrasonography could be a highly sensitive and specific tool for prediction of difficult intubation in OSA patients presented for elective surgery by measuring tongue base thickness, distance between lingual arteries, hyo-mental distance and condylar mobility.

Publications & conference data

No peer-reviewed publications indexed yet for this trial.