NCT05400031 is a NA clinical trial of propolis in Oral Mucositis, sponsored by Izmir Katip Celebi University.

Who is sponsoring NCT05400031?

NCT05400031 is sponsored by Izmir Katip Celebi University.

What drugs are being tested in NCT05400031?

Interventions in NCT05400031: propolis, Placebo.

What condition does NCT05400031 study?

NCT05400031 studies Oral Mucositis.

Is NCT05400031 still recruiting?

NCT05400031 is currently completed. Last updated 29 September 2023.

Last reviewed 2023-09-29 · How we verify

NCT05400031

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Oral Care With Propolis in Pediatric Oncology Patients

Completed NA Last updated 29 September 2023

What this trial tests

NA trial testing propolis in Oral Mucositis in 108 participants. Completed in 1 June 2023.

Timeline

1 June 2022

Primary endpoint
1 May 2023

1 June 2023

Quick facts

Lead sponsor	Izmir Katip Celebi University
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	triple
Primary purpose	prevention
Enrollment	108
Start date	1 June 2022
Primary completion	1 May 2023
Estimated completion	1 June 2023
Sites	1 location across Turkey (Türkiye)

Drugs / interventions tested

propolis — full drug profile →
Placebo

Conditions studied

Oral Mucositis — all drugs for Oral Mucositis →

Sponsor

Izmir Katip Celebi University

Who can join

Adults 2 to 18, any sex, with Oral Mucositis. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

According to the data from the World Health Organization, approximately 14 million people are diagnosed with cancer every year, and this number is expected to increase further in the next 10 years. Multidisciplinary treatment consisting of chemotherapy, radiotherapy and surgery is applied in childhood cancers. In chemotherapy, the target is cancerous cells, but high doses of chemotherapeutic agents do not have selectivity. Intact tissue cells are also affected by this cytotoxicity. Mucositis develops in the patient, especially as a result of the mucosal cells being affected. Mucositis is defined as damage to the mucosa lining the oral cavity, pharynx, larynx, oesophagus and gastrointestinal tract due to cancer treatment. It is one of the most important side effects of both chemotherapy and radiotherapy. This study is carried out to determine the effectiveness of propolis in preventing the formation of oral mucositis due to multiple use of chemotherapeutic drugs.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Propolis and Their Active Constituents for Chronic Diseases.
Chavda VP, Chaudhari AZ, Teli D, Balar P, et al · · 2023 · cited 18× · PMID 36830794 · DOI 10.3390/biomedicines11020259

Verify or expand the search:

Other trials of propolis

Trials testing the same drug.

NCT07073092 — Propolis for Management of Chemotherapy-Induced Oral Mucositis in Pediatric Patients · Phase 2 · not yet recruiting
NCT05625841 — Effects for Oral Mucositis Care During Chemoradiotherapy in Cancer Patients: Evaluation of the Bee Products · NA · unknown
NCT04916821 — Investigation of Clinical Effectiveness of Propolis Extracts as Food Supplements in Patients With SARS-CoV-2(COVID-19) · NA · unknown
NCT04843644 — Microbiota and Symptom Distress in Head and Neck Cancer Patients Receiving Radiotherapy · NA · unknown
NCT04382079 — Honey Products for Cancer Patients With Oral Mucositis: a Randomized Controlled Trial · NA · completed

Other recruiting trials for Oral Mucositis

Currently open trials in the same condition.

NCT07491536 — Ozone Therapy With Biomimetic Oral Care for Cancer-Related Oral Mucositis · NA · recruiting
NCT07400328 — Amimestrocel Injection for Preventing Severe Oral Mucositis in HSCT Patients · Phase 2 · recruiting
NCT06525402 — Effect of Sodium Bicarbonate, Saline and Black Mulberry Syrup on Degree of Oral Mucositis in Children Receiving Chemothe · NA · recruiting
NCT06315855 — F.L.O.S.S. Project (Facilitated Lessons on Oral and Systemic Health in Survivors) · NA · recruiting
NCT05966194 — RRx-001 for Reducing Oral Mucositis in Patients Receiving Chemotherapy and Radiation for Head and Neck Cancer · Phase 2 · recruiting

Other Izmir Katip Celebi University trials

Trials by the same sponsor.

NCT07460479 — Pilot Study of an Extended CBT Group Intervention for Intolerance of Uncertainty · NA · recruiting
NCT07453277 — Blood-Based Molecular Clock Biomarkers Predict Acute Ischemic Stroke Onset: A Prospective Observational Study · active not recruiting
NCT07341646 — Effect of Cuff Pressure Assessment Methods on Postoperative Complications in Breast Surgery · NA · not yet recruiting
NCT07304661 — Comparison of PPV and LVOT VTI During Passive Leg Raising to Predict Fluid Responsiveness · not yet recruiting
NCT07304648 — Role of End-Tidal CO2 During Passive Leg Raising to Predict Fluid Responsiveness in ICU · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT05400031 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Izmir Katip Celebi University
Last refreshed: 29 September 2023

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05400031.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing