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NCT05394428: STAR
A Multi Center Study of Sexual Toxicities After Radiotherapy
trial testing No intervention in Malignant Neoplasms in 300 participants. Currently enrolling.
31 August 2026
Quick facts
| Lead sponsor | Icahn School of Medicine at Mount Sinai |
|---|---|
| Status | Recruiting now |
| Study type | OBSERVATIONAL |
| Enrollment | 300 |
| Start date | 4 October 2022 |
| Primary completion | 31 August 2026 |
| Estimated completion | 31 August 2026 |
| Sites | 3 locations across United States |
Drugs / interventions tested
- No intervention
Conditions studied
- Malignant Neoplasms — all drugs for Malignant Neoplasms →
Sponsor
Icahn School of Medicine at Mount Sinai
Who can join
18 and older, female only, with Malignant Neoplasms. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The purpose of this research is to understand how radiotherapy and other cancer treatments impact sexual function in female cancer patients and to try to answer a question about why some patients who receive radiotherapy are more likely to have side effects than others. The results of this study may improve our understanding of why sexual side effects occur and in turn develop predictive models and biomarkers of sexual side effects and other side effects that may impact sexual function. The results of this study may also lead to improvements in the techniques used to deliver radiotherapy or the development of interventions that will prevent or reduce sexual side effects and improve quality of life for female patients with cancer.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
The Role of the Microbiome in Cancer Therapies: Current Evidence and Future Directions.
Chalif J, Goldstein N, Mehra Y, Spakowicz D, et al · · 2025 · cited 5× · PMID 39856008 · DOI 10.1016/j.hoc.2024.12.005
Verify or expand the search:
- PubMed search for NCT05394428
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Other recruiting trials for Malignant Neoplasms
Currently open trials in the same condition.
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Other Icahn School of Medicine at Mount Sinai trials
Trials by the same sponsor.
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- NCT07487948 — Safety and Biomarker Responses of Delgocitinib (JAK1,2,3/TYK2 Inhibitor) in Central Centrifugal Cicatricial Alopecia and · Phase 2 · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05394428 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Icahn School of Medicine at Mount Sinai
- Last refreshed: 22 November 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05394428.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing