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NCT05391581: GA-17
The Role of GIP and GLP-2 in Postprandial Splanchnic Blood Flow Distribution and Metabolism
NA trial testing GIPR antagonist / study tool in Blood Flow in 10 participants. Completed in 7 February 2023.
7 February 2023
Quick facts
| Lead sponsor | University of Copenhagen |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | crossover |
| Masking | single |
| Primary purpose | basic science |
| Enrollment | 10 |
| Start date | 13 January 2022 |
| Primary completion | 7 February 2023 |
| Estimated completion | 7 February 2023 |
| Sites | 1 location across Denmark |
Drugs / interventions tested
- GIPR antagonist / study tool
- GLP-2R antagonist / study tool
- Placebo
Conditions studied
- Blood Flow — all drugs for Blood Flow →
Sponsor
University of Copenhagen
Who can join
Adults 20 to 70, male only, with Blood Flow. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This project will describe the mechanisms of action and the relative contributions of GIP and GLP-2 to changes in gastrointestinal blood flow induced by oral glucose, exogenous GIP and GLP-2 infusions, and endogenous GIP and GLP-2 with the use of two novel receptor antagonists GIP(3-30)NH2 and GLP-2(3-33) in healthy individuals.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT05391581
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of GIPR antagonist / study tool
Trials testing the same drug.
- NCT06426823 — The Role of GIP in Postprandial Splanchnic Blood Flow Distribution and Metabolism in Patients With Type 2 Diabetes · NA · completed
Other recruiting trials for Blood Flow
Currently open trials in the same condition.
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- NCT06238609 — Neuromodulation for Prevention of Intensive Care Unit Acquired Weakness and Post Intensive Care Syndrome · NA · active not recruiting
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Other University of Copenhagen trials
Trials by the same sponsor.
- NCT07461324 — Surgeons' Prediction of Dental Surgery Complications and the Influence of Patient Characteristics: Development of an AI · not yet recruiting
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- NCT07450690 — Exercise Training Effects on Muscle Function in Adults With Mitochondrial Myopathy · NA · recruiting
- NCT07302880 — The Acute Interference of Biotin in Blood Analysis · NA · not yet recruiting
- NCT07312981 — The CPH-MBD Cohort Dietary Substudy - Comparison of Methods for Dietary Registrations · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05391581 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University of Copenhagen
- Last refreshed: 26 December 2023
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05391581.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing