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NCT05391087
Comparison Arterial Blood Pressure and Cardiac Index-based Hemodynamic Management on Postoperative Myocardial Injury
NA trial testing Mean arterial pressure based management in Myocardial Injury in 100 participants. Completed in 30 June 2023.
28 March 2023
Quick facts
| Lead sponsor | Istanbul Saglik Bilimleri University |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | prevention |
| Enrollment | 100 |
| Start date | 1 June 2022 |
| Primary completion | 28 March 2023 |
| Estimated completion | 30 June 2023 |
| Sites | 1 location across Turkey (Türkiye) |
Drugs / interventions tested
- Mean arterial pressure based management
- Cardiac index based management
Conditions studied
- Myocardial Injury — all drugs for Myocardial Injury →
- Perioperative/Postoperative Complications — all drugs for Perioperative/Postoperative Complications →
Sponsor
Istanbul Saglik Bilimleri University
Who can join
45 and older, any sex, with Myocardial Injury or Perioperative/Postoperative Complications. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The primary aim of this study is to compare mean arterial pressure (MAP) and cardiac index (CI) based intraoperative hemodynamic management in terms of postoperative high sensitive troponin elevation. The hypothesis of the study is that there will be at least 5ng/L difference between the two groups in terms of troponin elevation occurring in the postoperative period. When power analysis was performed with this primary output, it was calculated that while alpha was 0.05 beta 0.2, 42 patients in each group, a total of 84 patients were required.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Mean arterial pressure versus cardiac index for haemodynamic management and myocardial injury after hepatopancreatic surgery: A randomised controlled trial.
Abdullah T, Gökduman HC, Enişte İA, Kudaş İ, et al · · 2024 · cited 3× · PMID 39262319 · DOI 10.1097/eja.0000000000002059
Verify or expand the search:
- PubMed search for NCT05391087
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Other Istanbul Saglik Bilimleri University trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05391087 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Istanbul Saglik Bilimleri University
- Last refreshed: 5 July 2023
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05391087.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing