Last reviewed · How we verify
NCT05389787
Impact of Cerebellar TMS on Brain and Cognitive Functions in Schizophrenia: a Pilot Study
NA trial testing Transcranial Magnetic Stimulation in Schizophrenia in 40 participants. Currently enrolling.
31 August 2027
Quick facts
| Lead sponsor | Northwell Health |
|---|---|
| Phase | NA |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | factorial |
| Masking | double |
| Primary purpose | treatment |
| Enrollment | 40 |
| Start date | 18 August 2022 |
| Primary completion | 31 August 2027 |
| Estimated completion | 31 August 2027 |
| Sites | 1 location across United States |
Drugs / interventions tested
- Transcranial Magnetic Stimulation — full drug profile →
Conditions studied
- Schizophrenia — all drugs for Schizophrenia →
- Cerebellar Function — all drugs for Cerebellar Function →
- Condition — all drugs for Condition →
Sponsor
Northwell Health — full company profile →
Who can join
Adults 18 to 60, any sex, with Schizophrenia or Cerebellar Function. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This is a single-site, sham-controlled, randomized trial in a total of 40 subjects between ages 18 and 60 years with schizophrenia. This study will investigate the effects of 4-week rTMS treatment on brain and cognitive functions in patients. Subjects will be randomized to one of the following arms: Arm 1: Standard of Care (SOC) and active rTMS Arm 2: Standard of Care (SOC) and sham rTMS Each participant will receive rTMS five days per week, for four consecutive weeks. Functional magnetic resonance imaging (fMRI) scans, clinical assessments, and cognitive tests will be performed at baseline, end of the 2nd week, and end of the 4th week.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Illuminating posterior targets for TMS beyond the prefrontal cortex.
McCalley DM, Sanderson LL, Dowdle LT, Padula CB, et al · · 2025 · cited 1× · PMID 42145912 · DOI 10.1038/s44220-025-00433-3
Verify or expand the search:
- PubMed search for NCT05389787
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05389787 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Northwell Health
- Last refreshed: 25 September 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05389787.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing