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NCT05382260
Personal Music for Disorders of Consciousness
NA trial testing Listening to music in Disorder of Consciousness in 45 participants. Status unknown.
31 December 2023
Quick facts
| Lead sponsor | Qiuyou Xie |
|---|---|
| Phase | NA |
| Status | Status unknown |
| Study type | INTERVENTIONAL |
| Allocation | non randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 45 |
| Start date | 26 May 2022 |
| Primary completion | 31 December 2023 |
| Estimated completion | 31 December 2023 |
| Sites | 1 location across China |
Drugs / interventions tested
- Listening to music
Conditions studied
- Disorder of Consciousness — all drugs for Disorder of Consciousness →
Sponsor
Qiuyou Xie
Who can join
Adults 18 to 70, any sex, with Disorder of Consciousness. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Background: The evaluation and treatment of disorders of consciousness(DOC) is a challenging undertaking. Now many neuroimaging techniques were used to detect the level of consciousness and electroencephagram(EEG) was widely used because of its high temporal resolution. Music would be an effective for DOC, due to its highly arousal value. Preferred music was near to persons, so that it would excite more range of cortical and increase the functional connectivity between cortices. Methods: The exploratory study included 15 health controls and 30 DOC, with 15 minimally conscious state(MCS) and 15 vegetative state(VS). After 5 minutes baseline silence, they listened to relaxing music(RM), preferred music(PM) and amplitude modulated sound(AMS), with 5 minutes baseline silence in the end, meanwhile EEG recorded their cortical activity. Each music was appropriately 5 minutes and separated by 3 minutes washout. Discussion: The study would verify the effect of preferred music to the functional connectivity of DOC. Music would excite the networks related to consciousness by cross-modal.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Individualized music induces theta-gamma phase-amplitude coupling in patients with disorders of consciousness.
Xiao Q, Zheng X, Wen Y, Yuan Z, et al · · 2024 · cited 3× · PMID 39010944 · DOI 10.3389/fnins.2024.1395627
Verify or expand the search:
- PubMed search for NCT05382260
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
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Trials testing the same drug.
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- NCT06187272 — Effectiveness of Music Practical Examinations · NA · completed
- NCT04518917 — Sing for Your Saunter - Dementia Supplement · NA · completed
- NCT04246476 — Sing for Your Saunter · NA · completed
Other recruiting trials for Disorder of Consciousness
Currently open trials in the same condition.
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- NCT06515132 — Efficacy and Safety of Spinal Cord Stimulation in Patients With Spinal Cord Stimulation · NA · recruiting
- NCT06469983 — Robotic vs. Traditional Verticalization in Patients With Severe Acquired Brain Injury: a Randomized Controlled Trial · NA · recruiting
- NCT06527573 — Effects of rTMS With Different Stimulation Spots in Patients With Disorders of Consciousness · NA · recruiting
- NCT06635291 — Improving the Diagnostic Accuracy of Children with DoC (IDeAl DesiRE) · recruiting
Other Qiuyou Xie trials
Trials by the same sponsor.
- NCT05943431 — taVNS Paired With Motor Training for Upper-extremity Rehabilitation in Stroke Patients · NA · unknown
- NCT05187000 — Effects of Individualized rTMS in DOC Patients · NA · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05382260 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Qiuyou Xie
- Last refreshed: 23 January 2023
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05382260.
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