Last reviewed · How we verify
NCT05368532
Excitability Protocol: Voltage-gated Ion Channels
NA trial testing Temperature in Pain in 30 participants. Status unknown.
1 December 2023
Quick facts
| Lead sponsor | Aalborg University |
|---|---|
| Phase | NA |
| Status | Status unknown |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | basic science |
| Enrollment | 30 |
| Start date | 31 July 2022 |
| Primary completion | 1 December 2023 |
| Estimated completion | 1 March 2024 |
| Sites | 1 location across Denmark |
Drugs / interventions tested
- Temperature
Conditions studied
- Pain — all drugs for Pain →
Sponsor
Aalborg University
Who can join
Adults 18 to 80, any sex, with Pain. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The purpose of subproject 1 is to evaluate the accuracy of a nerve excitability protocol in healthy subjects before testing the protocol in diabetic neuropathy patients. The nerve excitability protocol has been derived by computational modeling to identify abnormalities of three subtypes of ion voltage-gated channels. These three ion channels are all altered in animal models of diabetic neuropathy and, therefore, are likely candidates for generating the altered excitability in diabetic neuropathy patients. The hypothesis for subproject 1 is that due to the unique dynamics of each subtype of voltage-gated ion channels, it is possible to identify abnormal voltage-gated ion channel alterations by altering the shape of the electrical stimulation.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT05368532
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Temperature
Trials testing the same drug.
- NCT06313385 — Investigating the Impact of Indocyanine Green Titration on Fluorescent Intensity in Free Flap : An Exploration of Altern · NA · unknown
- NCT06405282 — Weightlessness Associated Cephalad Fluid Shifts; The Potential to Evaluate Venous and Lymphatic Dysfunction · completed
- NCT05193422 — Protective Face Masks and Cardiopulmonary Parameters at Rest and During Exercise in Children · NA · unknown
- NCT03860402 — The Effect of Warm Local Anesthetic Solution on Epidural Anesthesia · completed
- NCT03700164 — The Effect of Cold Exposure on Glucose Tolerance · NA · completed
Other recruiting trials for Pain
Currently open trials in the same condition.
- NCT07533409 — Tactile and Pain Sensory Thresholds and Hand Grip Strength · recruiting
- NCT07294092 — Ketamine and Propofol NeuroImaging · EARLY_PHASE1 · recruiting
- NCT07290205 — Remimazolam NeuroImaging · EARLY_PHASE1 · recruiting
- NCT07487610 — Relationship Between Neuropathic Pain and Geriatric Assessment Parameters in Patients Aged 80 Years and Older · recruiting
- NCT07454993 — The Effect of Music During Colonoscopy · NA · recruiting
Other Aalborg University trials
Trials by the same sponsor.
- NCT07580989 — Network Effects of Left M1 rTMS: A TMS-EEG Study · NA · recruiting
- NCT07395882 — A New Model to Induce Itch and Inflammation · NA · not yet recruiting
- NCT07395869 — Off-set Analgesia Induced by Cold Temperature · NA · not yet recruiting
- NCT07266103 — Mechanistic Study of Personalized rTMS in Chronic Pain · NA · not yet recruiting
- NCT07373392 — Effects of LP-LDL® on Lipid Metabolism, Glycemic Control, Inflammatory Markers, and Cognitive Function in Individuals Wi · NA · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05368532 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Aalborg University
- Last refreshed: 2 August 2023
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05368532.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing