Who is sponsoring NCT05357638?

NCT05357638 is sponsored by Amsterdam UMC, location VUmc.

What drugs are being tested in NCT05357638?

Interventions in NCT05357638: High Intensity Interval Training (HIIT), Continuous Aerobic Training (CAT), Movement Advice.

What condition does NCT05357638 study?

NCT05357638 studies Parkinson Disease, Multiple Sclerosis.

Is NCT05357638 still recruiting?

NCT05357638 is currently status unknown. Last updated 25 April 2023.

Last reviewed 2023-04-25 · How we verify

NCT05357638: HersenFIT

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Physical Training for People With Parkinson's Disease and Multiple Sclerosis: Effect on Mind and Body

Status unknown NA Last updated 25 April 2023

What this trial tests

NA trial testing High Intensity Interval Training (HIIT) in Parkinson Disease in 48 participants. Status unknown.

Timeline

2 May 2022

Primary endpoint
2 May 2025

2 November 2025

Quick facts

Lead sponsor	Amsterdam UMC, location VUmc
Phase	NA
Status	Status unknown
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	single
Primary purpose	treatment
Enrollment	48
Start date	2 May 2022
Primary completion	2 May 2025
Estimated completion	2 November 2025
Sites	1 location across Netherlands

Drugs / interventions tested

High Intensity Interval Training (HIIT)
Continuous Aerobic Training (CAT)
Movement Advice

Conditions studied

Parkinson Disease — all drugs for Parkinson Disease →
Multiple Sclerosis — all drugs for Multiple Sclerosis →

Sponsor

Amsterdam UMC, location VUmc — full company profile →

Who can join

18 and older, any sex, with Parkinson Disease or Multiple Sclerosis. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

People with Parkinson's disease and Multiple Sclerosis experience disabling motor and non-motor symptoms, which respond insufficiently to medication. To adequately alleviate disease burden, physical training is increasing acknowledged as an assisting therapy; however, the optimal dose of exercise in unknown.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

(HIIT-The Track) High-Intensity Interval Training for People with Parkinson's Disease: Individual Response Patterns of (Non-)Motor Symptoms and Blood-Based Biomarkers-A Crossover Single-Case Experimental Design.
Gomes ESA, Van den Heuvel OA, Rietberg MB, De Groot V, et al · · 2023 · cited 5× · PMID 37371330 · DOI 10.3390/brainsci13060849
HIITing Anxiety and Depression in Parkinson's Disease and Multiple Sclerosis-A Study Protocol of a Transdiagnostic Randomized Controlled Trial (HersenFIT).
Gravesteijn AS, Rietberg MB, de Groot V, Hirsch MA, et al · · 2025 · cited 1× · PMID 41008305 · DOI 10.3390/brainsci15090945

Verify or expand the search:

Other trials of High Intensity Interval Training (HIIT)

Trials testing the same drug.

NCT06831266 — Effects of Exercise Prediabetic Individuals · NA · recruiting
NCT06551441 — Cardiopulmonary Adaptations to High-intensity Interval Training (HIIT) in COPD · NA · recruiting
NCT06609954 — "COMPARATIVE EFFECTS of REDUCED EXERTION HIGH INTENSITY TRAINING (REHIT) VERSUS HIGH INTENSITY INTERVAL TRAINING (HIIT) · NA · active not recruiting
NCT06610006 — Combined Effects of Isometric Wall Squats and High Intensity Interval Training on Rate Pressure Product in Normotensive · NA · active not recruiting
NCT06059872 — Biomarkers of Reaction To HIIT Exercise · NA · recruiting

Other recruiting trials for Parkinson Disease

Currently open trials in the same condition.

NCT07399496 — Accelerated TMS for Apathy in PD · NA · recruiting
NCT07371338 — Phase 1 Clinical Trial to Evaluate the Safety, Efficacy, and Pharmacokinetics of IPS101A in Parkinson's Disease Patients · Phase 1 · recruiting
NCT07442370 — The Effect of Functional Rotational Exercises on Fall Risk and Mobility in Parkinson's Disease Patients · NA · recruiting
NCT06848205 — Percept Transitions in FOG and PD · NA · recruiting
NCT07432958 — A Study to Evaluate the Effectiveness of Two Doses of AP-472 as Adjunctive Therapy to Levodopa in Parkinson's Disease (P · Phase 2 · recruiting

Other Amsterdam UMC, location VUmc trials

Trials by the same sponsor.

NCT07470697 — Deep Relaxation Using Virtual Reality Intervention Before Surgery for Healthcare Professionals Working in the Operating · NA · not yet recruiting
NCT07278206 — Brain Stimulation in Long COVID · NA · recruiting
NCT07155681 — Evaluating Healthcare Professionals' Satisfaction and Stress Mitigation Using Virtual Reality Intervention in Surgical W · NA · not yet recruiting
NCT06416345 — Cue2Walk, Cost-effectiveness of Automated Freezing Detection and Provision of External Cues in Comparison to Usual Care · NA · recruiting
NCT06658522 — Right Ventricular Compensation With Sotatercept: A Prospective Single Arm Open Label Phase 4 Study to Evaluate the Effec · Phase 4 · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT05357638 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Amsterdam UMC, location VUmc
Last refreshed: 25 April 2023

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05357638.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing