Last reviewed · How we verify
NCT05331456: ACROSTIC
Alveolar Cleft Repair Using Osteoinductive Ceramics
NA trial testing Unilateral alveolar cleft repair in Cleft Palate Children in 60 participants. Status unknown.
1 February 2025
Quick facts
| Lead sponsor | UMC Utrecht |
|---|---|
| Phase | NA |
| Status | Status unknown |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | treatment |
| Enrollment | 60 |
| Start date | 1 June 2022 |
| Primary completion | 1 February 2025 |
| Estimated completion | 1 February 2025 |
| Sites | 4 locations across Netherlands |
Drugs / interventions tested
- Unilateral alveolar cleft repair
Conditions studied
- Cleft Palate Children — all drugs for Cleft Palate Children →
- Cleft Alveolar Ridge — all drugs for Cleft Alveolar Ridge →
- Cleft Lip and Palate — all drugs for Cleft Lip and Palate →
Sponsor
UMC Utrecht — full company profile →
Who can join
Adults 8 to 12, any sex, with Cleft Palate Children or Cleft Alveolar Ridge. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
In this study, patients with unilateral cleft lip and palate are enrolled in a multicenter stepped wedge randomized trial ithat compares alveolar cleft closure using autologous bone harvested form the mandibular symphysis with an osteoinductive biphasic calcium phosphate putty.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT05331456
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Unilateral alveolar cleft repair
Trials testing the same drug.
- NCT07066293 — Sticky Bone Grafting With Concentrated Growth Factor Membrane for Repair of Unilateral Alveolar Cleft · NA · completed
Other recruiting trials for Cleft Palate Children
Currently open trials in the same condition.
- NCT06505330 — Respiratory Tract Microbiome and Probiotics in Children With Cleft Palate · NA · recruiting
- NCT06143254 — Effect of Infant Sign Training on Speech-language Development · NA · recruiting
- NCT06105099 — Effect of Performance-specific Cleft Speech Intervention and Long-term Learning in Children With a Cleft Palate · NA · recruiting
- NCT07279883 — Length of Hospital Stay and Postoperative Analgesic Requirements After Introduction of a Specific Maxillary Nerve Block · recruiting
Other UMC Utrecht trials
Trials by the same sponsor.
- NCT07512336 — A Randomized Intra-Patient Controlled Trial of MagnetOs™ Putty vs Autograft in Instrumented Posterolateral Spinal Fusion · NA · not yet recruiting
- NCT07485985 — Coronary Sinus Reducer Therapy for Persisting Angina · NA · not yet recruiting
- NCT07449052 — Comprehensive Invasive Physiological Evaluation of Obstructive Coronary Artery Disease · NA · not yet recruiting
- NCT05375708 — Systemic Therapy in Combination with Stereotactic Radiotherapy in Patients with Metastatic Colorectal Cancer Up to 10 Me · Phase 2 · suspended
- NCT06898541 — Coronary Sinus Reducer in Coronary Microvascular Disease · NA · enrolling by invitation
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05331456 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by UMC Utrecht
- Last refreshed: 6 December 2023
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05331456.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing