All registered antiepileptic drugs · Neurology Antiepileptic drugs work through multiple mechanisms including sodium channel blockade, GABA enhancement, calcium channel modulation, and other pathways to reduce neuronal excitability and prevent seizures.
Intermediate dose thromboprophylaxis · Cardiovascular Intermediate dose thromboprophylaxis uses anticoagulants at moderate doses to prevent blood clot formation in patients at intermediate risk.
Mild stimulation · Neurology Mild stimulation drugs work by increasing alertness and energy levels through the activation of certain neurotransmitters in the brain.
Progesterone Vaginal Product · Reproductive Health / Obstetrics Progesterone binds to progesterone receptors in the reproductive tract to support luteal phase function and maintain pregnancy.
simvastatin and ezetimibe · Cardiovascular Simvastatin inhibits cholesterol synthesis while ezetimibe blocks dietary cholesterol absorption, together reducing LDL cholesterol levels.
Phase 3 pipeline
ARB + DMX-200 · Cardiovascular ARB + DMX-200 combines an angiotensin II receptor blocker with DMX-200, a drug delivery technology designed to enhance therapeutic efficacy and potentially reduce adverse effects.
Combined aspirin and multinutrient supplement · Cardiovascular Aspirin reduces platelet aggregation and inflammation while multinutrients provide essential vitamins and minerals to support cardiovascular health and metabolic function.
Continuation of therapeutic dose anticoagulation · Cardiovascular Continuation of therapeutic-dose anticoagulation maintains inhibition of blood coagulation cascade to prevent thrombotic events.
Conventional low dose thromboprophylaxis · Cardiovascular Conventional low-dose thromboprophylaxis prevents blood clot formation by inhibiting coagulation cascade factors, typically using anticoagulants at reduced doses for prevention rather than treatment.
Delayed administration of convalescent plasma · Immunology/Infectious Disease Convalescent plasma transfers antibodies and immune factors from recovered patients to provide passive immunotherapy against infectious disease.
Extended course macrolide · Respiratory/Pulmonology Extended course macrolide antibiotics reduce airway inflammation and modulate immune responses in chronic respiratory conditions through anti-inflammatory and immunomodulatory effects.
Five-days oseltamivir · Infectious Disease Oseltamivir is a neuraminidase inhibitor that blocks the release of influenza virus particles from infected cells, reducing viral spread.
Five-days oseltamivir + baloxavir marboxil · Infectious Disease / Virology This combination uses two antiviral agents with different mechanisms to inhibit influenza virus replication through dual targeting of viral neuraminidase and cap-dependent endonuclease.
Fixed-duration dexamethasone · Immunology Dexamethasone is a corticosteroid that suppresses immune and inflammatory responses by binding to glucocorticoid receptors and modulating gene expression.
Fixed-duration higher dose Hydrocortisone · Immunology / Critical Care / Inflammation Hydrocortisone is a glucocorticoid that suppresses immune and inflammatory responses by binding to glucocorticoid receptors and modulating cytokine production.
Fixed-duration Hydrocortisone · Immunology / Endocrinology Fixed-duration hydrocortisone provides short-term glucocorticoid replacement or anti-inflammatory effects with a predetermined treatment duration to minimize long-term steroid exposure.
Gallium-68-tilmanocept · Oncology; Infectious Disease; Inflammation Imaging Gallium-68-tilmanocept is a radioactive imaging agent that binds to mannose receptors on immune cells to visualize inflammation and infection sites.
Hydroxychloroquine + lopinavir/ritonavir · Infectious Disease / Virology This combination uses hydroxychloroquine to modulate immune response and autophagy while lopinavir/ritonavir inhibits viral protease to reduce viral replication.
Local standard venous thromboprophylaxis · Cardiovascular Local standard venous thromboprophylaxis prevents blood clots in veins through established anticoagulant or mechanical methods applied according to institutional protocols.
Moxifloxacin or Levofloxacin · Infectious Diseases Moxifloxacin and Levofloxacin are broad-spectrum antibiotics that inhibit DNA gyrase and topoisomerase IV, enzymes critical for bacterial DNA replication.
Nirmatrelvir/ritonavir + remdesivir · Infectious Disease / Virology This combination uses nirmatrelvir/ritonavir to inhibit SARS-CoV-2 protease and remdesivir to inhibit viral RNA polymerase, targeting two critical steps of viral replication.
Shock-dependent hydrocortisone · Critical Care Shock-dependent hydrocortisone is a corticosteroid that is administered in response to shock to reduce inflammation and support the body's response to stress.
Standard course macrolide · Infectious disease Macrolides inhibit bacterial protein synthesis by binding to the 50S ribosomal subunit.
Ten-days oseltamivir · Infectious Disease Oseltamivir is a neuraminidase inhibitor that blocks the release of influenza virus particles from infected cells, reducing viral spread.
Ten-days oseltamivir + baloxavir marboxil · Infectious Diseases Oseltamivir is a neuraminidase inhibitor that blocks the release of influenza virus from infected cells, while baloxavir marboxil is a cap-dependent endonuclease inhibitor that blocks viral replication.