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NCT05319392: GAC
Transcriptomic Signatures in Gastric Adenocarcinoma
trial testing Observational study in Gastric Adenocarcinoma in 48 participants. Status unknown.
6 April 2025
Quick facts
| Lead sponsor | Sanjay Gandhi Postgraduate Institute of Medical Sciences |
|---|---|
| Status | Status unknown |
| Study type | OBSERVATIONAL |
| Enrollment | 48 |
| Start date | 6 August 2021 |
| Primary completion | 6 April 2025 |
| Estimated completion | 6 October 2025 |
| Sites | 1 location across India |
Drugs / interventions tested
- Observational study — full drug profile →
Conditions studied
- Gastric Adenocarcinoma — all drugs for Gastric Adenocarcinoma →
Sponsor
Sanjay Gandhi Postgraduate Institute of Medical Sciences
Who can join
Adults 18 to 80, any sex, with Gastric Adenocarcinoma. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Gastric Adenocarcinoma (GAC) accounting for the major percentage of all stomach malignancies is associated with a poor overall survival of 25-30% despite the advancement in treatment strategies. Several factors associated with tumor microenvironment (TME) are thought to play an important role in tumorigenesis and acquired chemoresistance to therapies that are not otherwise addressed by the comprehensive molecular classification of GAC given by TCGA and ACRG. In the present study investigators intend to do transcriptome profiling of GAC tumor tissue and adjacent normal tissue to investigate differentially expressed genes between the two in relation to TME which might help in identification of gene signatures that are clinically relevant with survival outcome in Gastric Adenocarcinoma.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Bioinformatics Analysis and Validation of Potential Markers Associated with Prediction and Prognosis of Gastric Cancer.
Matsuoka T, Yashiro M. · · 2024 · cited 46× · PMID 38892067 · DOI 10.3390/ijms25115880
Verify or expand the search:
- PubMed search for NCT05319392
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Other Sanjay Gandhi Postgraduate Institute of Medical Sciences trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05319392 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Sanjay Gandhi Postgraduate Institute of Medical Sciences
- Last refreshed: 15 April 2022
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05319392.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing