NCT05311254 (FOVOCIP) is a Phase 3 clinical trial of Fosfomycin Calcium in Febrile Neutropenia, sponsored by Fundación para la Investigación Biosanitaria del Principado de Asturias.

Who is sponsoring NCT05311254?

NCT05311254 is sponsored by Fundación para la Investigación Biosanitaria del Principado de Asturias.

What drugs are being tested in NCT05311254?

Interventions in NCT05311254: Fosfomycin Calcium.

What condition does NCT05311254 study?

NCT05311254 studies Febrile Neutropenia.

Is NCT05311254 still recruiting?

NCT05311254 is currently status unknown. Last updated 14 September 2023.

Last reviewed 2023-09-14 · How we verify

NCT05311254: FOVOCIP

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

A Trial of Fosfomycin vs Ciprofloxacin for Febrile Neutropenia

Status unknown Phase 3 Last updated 14 September 2023

What this trial tests

Phase 3 trial testing Fosfomycin Calcium in Febrile Neutropenia in 156 participants. Status unknown.

Timeline

14 March 2022

Primary endpoint
14 March 2024

14 March 2024

Quick facts

Lead sponsor	Fundación para la Investigación Biosanitaria del Principado de Asturias
Phase	Phase 3
Status	Status unknown
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	none
Primary purpose	prevention
Enrollment	156
Start date	14 March 2022
Primary completion	14 March 2024
Estimated completion	14 March 2024
Sites	1 location across Spain

Drugs / interventions tested

Fosfomycin Calcium

Conditions studied

Febrile Neutropenia — all drugs for Febrile Neutropenia →

Sponsor

Fundación para la Investigación Biosanitaria del Principado de Asturias

Who can join

18 and older, any sex, with Febrile Neutropenia. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Randomized phase 3 trial to compare efficacy and safety of oral fosfomycin versus ciprofloxacin to prevent febrile neutropenia in patients with acute leukemia or recipients of hematopoietic stem cell transplant.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

FOVOCIP study: a multicenter randomized trial of fosfomycin versus ciprofloxacin for febrile neutropenia in hematologic patients-efficacy and microbiologic safety.
Moreno AF, Lavín-Alconero L, de Ugarriza PL, Blanco LS, et al · · 2023 · cited 1× · PMID 37891616 · DOI 10.1186/s13063-023-07702-5
Fosfomycin versus ciprofloxacin for febrile neutropenia prophylaxis in high-risk haematological patients (FOVOCIP): a phase 3, open-label, multicentre, randomised, non-inferiority trial.
Moreno AF, López de Ugarriza P, González Huerta AJ, Pascual BB, et al · · 2026 · PMID 42164340 · DOI 10.1016/j.lanepe.2026.101698

Verify or expand the search:

Other recruiting trials for Febrile Neutropenia

Currently open trials in the same condition.

NCT07204522 — Efficacy of Empirical Anti-Infective Therapy in Neutropenic Febrile Patients. · recruiting
NCT05815628 — Next-Generation-Sequencing Approach to Neutropenic Sepsis · recruiting
NCT06787326 — Effect of the BioFire FilmArray (BCID2) for the Rapid Detection of Bloodstream Infection in Haematologic Patients With F · active not recruiting
NCT05786495 — Short Antibiotic Treatment in High Risk Febrile Neutropenia · NA · recruiting

Other Fundación para la Investigación Biosanitaria del Principado de Asturias trials

Trials by the same sponsor.

NCT06282042 — Early Transcatheter Mitral Valve Repair After Myocardial Infarction · NA · recruiting
NCT06614595 — Transfusion in Lower Risk MDS Patients: Predictors of Adequacy of Transfusion and Quality of Life in Lower Risk MDS · recruiting
NCT04838938 — Personalized Medicine in Patients With Infective Endocarditis · completed
NCT04660448 — Lung Ultrasound Score and Pediatric Intensive Care Outcomes (LUS-PICO) · completed
NCT05518786 — Precision Medicine for Post-Intensive Care Syndrome (PreMed4PICS) · unknown

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT05311254 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Fundación para la Investigación Biosanitaria del Principado de Asturias
Last refreshed: 14 September 2023

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05311254.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing