NCT04660448 (LUS-PICO) is a clinical trial of Bedside lung ultrasound examination in Lung Injury, sponsored by Fundación para la Investigación Biosanitaria del Principado de Asturias.

Who is sponsoring NCT04660448?

NCT04660448 is sponsored by Fundación para la Investigación Biosanitaria del Principado de Asturias.

What drugs are being tested in NCT04660448?

Interventions in NCT04660448: Bedside lung ultrasound examination.

What condition does NCT04660448 study?

NCT04660448 studies Lung Injury, Extravascular Lung Water, Pulmonary Edema, Acute Respiratory Distress Syndrome, Shock.

Is NCT04660448 still recruiting?

NCT04660448 is currently completed. Last updated 12 April 2022.

Last reviewed 2022-04-12 · How we verify

NCT04660448: LUS-PICO

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Lung Ultrasound Score and Pediatric Intensive Care Outcomes (LUS-PICO)

Completed Last updated 12 April 2022

What this trial tests

trial testing Bedside lung ultrasound examination in Lung Injury in 650 participants. Completed in 30 November 2021.

Timeline

1 December 2020

Primary endpoint
31 March 2021

30 November 2021

Quick facts

Lead sponsor	Fundación para la Investigación Biosanitaria del Principado de Asturias
Status	Completed
Study type	OBSERVATIONAL
Enrollment	650
Start date	1 December 2020
Primary completion	31 March 2021
Estimated completion	30 November 2021
Sites	1 location across Spain

Drugs / interventions tested

Bedside lung ultrasound examination

Conditions studied

Lung Injury — all drugs for Lung Injury →
Extravascular Lung Water — all drugs for Extravascular Lung Water →
Pulmonary Edema — all drugs for Pulmonary Edema →
Acute Respiratory Distress Syndrome — all drugs for Acute Respiratory Distress Syndrome →

Sponsor

Fundación para la Investigación Biosanitaria del Principado de Asturias

Who can join

Adults 1 Month to 18, any sex, with Lung Injury or Extravascular Lung Water. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Bedside lung ultrasonography helps to obtain reliable clinical information about lung aeration, that has been categorized by means of the so-called lung ultrasound score (LUS). In critically ill adults, LUS has been related with the outcome both in patients with respiratory and some non-respiratory conditions. Pediatric studies about lung aeration have been done mainly on postoperative cardiac patients and infants with bronchiolitis. In this prospective, observational, multicenter, feasibility and diagnostic accuracy study, we will explore the degree of lung aeration impairment as a potential outcome predictor in critically ill children with a variety of underlying conditions. Children from 1 month to 18 years of age admitted to PICU will be recruited and LUS will be calculated at two time points: at 12 ± 6 hours and at 48-72 hours. Univariate and multivariate statistical analysis will be performed in order to ascertain the outcome influence of clinical factors in general and LUS in particular.

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.

Verify or expand the search:

Other recruiting trials for Lung Injury

Currently open trials in the same condition.

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Other Fundación para la Investigación Biosanitaria del Principado de Asturias trials

Trials by the same sponsor.

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NCT06614595 — Transfusion in Lower Risk MDS Patients: Predictors of Adequacy of Transfusion and Quality of Life in Lower Risk MDS · recruiting
NCT05311254 — A Trial of Fosfomycin vs Ciprofloxacin for Febrile Neutropenia · Phase 3 · unknown
NCT04838938 — Personalized Medicine in Patients With Infective Endocarditis · completed
NCT05518786 — Precision Medicine for Post-Intensive Care Syndrome (PreMed4PICS) · unknown

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04660448 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Fundación para la Investigación Biosanitaria del Principado de Asturias
Last refreshed: 12 April 2022

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04660448.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing