Who is sponsoring NCT05296499?

NCT05296499 is sponsored by Guy's and St Thomas' NHS Foundation Trust.

What drugs are being tested in NCT05296499?

Interventions in NCT05296499: Cardiopulmonary exercise test (CPET), Exercise cardiac MRI, 6 minute walk test, Blood tests, Quality of life questionnaires, Repeat baseline assessments, MR venogram.

What condition does NCT05296499 study?

NCT05296499 studies Venous Thrombosis Deep (Limbs), Post Thrombotic Syndrome.

Is NCT05296499 still recruiting?

NCT05296499 is currently status unknown. Last updated 25 March 2022.

Last reviewed 2022-03-25 · How we verify

NCT05296499

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

EXERT: Exercise Physiology After Thrombosis

Status unknown Last updated 25 March 2022

What this trial tests

trial testing Cardiopulmonary exercise test (CPET) in Venous Thrombosis Deep (Limbs) in 56 participants. Status unknown.

Timeline

20 September 2019

Primary endpoint
20 October 2022

20 April 2023

Quick facts

Lead sponsor	Guy's and St Thomas' NHS Foundation Trust
Status	Status unknown
Study type	OBSERVATIONAL
Enrollment	56
Start date	20 September 2019
Primary completion	20 October 2022
Estimated completion	20 April 2023
Sites	1 location across United Kingdom

Drugs / interventions tested

Cardiopulmonary exercise test (CPET)
Exercise cardiac MRI
6 minute walk test
Blood tests — full drug profile →
Quality of life questionnaires
Repeat baseline assessments
MR venogram

Conditions studied

Venous Thrombosis Deep (Limbs) — all drugs for Venous Thrombosis Deep (Limbs) →
Post Thrombotic Syndrome — all drugs for Post Thrombotic Syndrome →

Sponsor

Guy's and St Thomas' NHS Foundation Trust

Who can join

16 and older, any sex, with Venous Thrombosis Deep (Limbs) or Post Thrombotic Syndrome. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Deep vein thrombosis (DVT) can cause long-term scarring and narrowing of veins. When there is extensive damage to the veins in the legs, groin or abdomen it can affect the way that blood is able to flow back up to the heart. Some patients are left with severe symptoms such as pain, leg swelling and ulcers, and have surgical treatment with nitinol stents to re-open the veins and relieve symptoms. The primary aim of this study is to investigate venous blood flow to the heart during exercise in patients with extensive damage to the veins in the groin and abdomen after DVT, and changes that happen after stenting.

Publications & conference data

No peer-reviewed publications indexed yet for this trial.

Verify or expand the search:

Other trials of Cardiopulmonary exercise test (CPET)

Trials testing the same drug.

NCT06796530 — High Intensity Exercise in Children With MCADD · NA · completed
NCT05205642 — Exercise Fatigue Parameters and Endothelial Function in Pediatric Patients With a History of COVID-19 Infection or MIS-C · NA · unknown
NCT05323760 — Functional Capacity in Patients Post Mild COVID-19 · NA · unknown
NCT04195061 — Relative Sarcopenia and Cardiometabolic Risk in Young Adults With Obesity · completed
NCT04312802 — Cardiopulmonary Testing for Potential Pancreas Transplant Candidates · completed

Other Guy's and St Thomas' NHS Foundation Trust trials

Trials by the same sponsor.

NCT07534917 — Comparing the Effects of Newer Pacemakers and Their Effects on the Heart and Valve Function in the Short-term. · not yet recruiting
NCT07454135 — Mechanisms of Atrial Pathoelectrophysiology in HCM · not yet recruiting
NCT07419945 — Older Kidney Patient Optimisation Pretransplant · NA · not yet recruiting
NCT07309835 — Improving Genetic Medicine for Ethnic Minority Groups · not yet recruiting
NCT07203872 — Inflammation-resolution Therapy in MINST of Periodontal Intrabony Defect: a Pilot Randomised Controlled Trial · NA · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT05296499 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Guy's and St Thomas' NHS Foundation Trust
Last refreshed: 25 March 2022

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05296499.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing