NCT05280366 (VENICE) is a NA clinical trial of Streamline Surgical System in Open Angle Glaucoma, sponsored by New World Medical, Inc..

Who is sponsoring NCT05280366?

NCT05280366 is sponsored by New World Medical, Inc..

What drugs are being tested in NCT05280366?

Interventions in NCT05280366: Streamline Surgical System, iStent Inject W.

What condition does NCT05280366 study?

NCT05280366 studies Open Angle Glaucoma.

Is NCT05280366 still recruiting?

NCT05280366 is currently active, enrolled. Last updated 12 November 2024.

Last reviewed 2024-11-12 · How we verify

NCT05280366: VENICE

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

STREAMLINE®SURGICAL SYSTEM Compared to iStent Inject W® in Patients With Open-Angle Glaucoma

Active, enrolled NA Last updated 12 November 2024

What this trial tests

NA trial testing Streamline Surgical System in Open Angle Glaucoma in 150 participants. Participants enrolled and being followed up; not accepting new ones.

Timeline

9 February 2022

Primary endpoint
30 June 2026

30 June 2026

Quick facts

Lead sponsor	New World Medical, Inc.
Phase	NA
Status	Active, enrolled
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	single
Primary purpose	treatment
Enrollment	150
Start date	9 February 2022
Primary completion	30 June 2026
Estimated completion	30 June 2026
Sites	20 locations across Costa Rica, United States, Mexico

Drugs / interventions tested

Streamline Surgical System
iStent Inject W

Conditions studied

Open Angle Glaucoma — all drugs for Open Angle Glaucoma →

Sponsor

New World Medical, Inc. — full company profile →

Who can join

22 and older, any sex, with Open Angle Glaucoma. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

A study of the Streamline Surgical System versus competitor

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

A Randomized Controlled Trial Comparing STREAMLINE Canaloplasty to Trabecular Micro-Bypass Stent Implantation in Primary Open-Angle Glaucoma.
Goldberg DF, Orlich C, Flowers BE, Singh IP, et al · · 2024 · cited 3× · PMID 39429442 · DOI 10.2147/opth.s481945

Verify or expand the search:

Other trials of Streamline Surgical System

Trials testing the same drug.

NCT05089474 — A First in Human Clinical Trial to Evaluate the Safety and Effectiveness of the STREAMLINE SURGICAL SYSTEM in Patients W · NA · completed

Other recruiting trials for Open Angle Glaucoma

Currently open trials in the same condition.

NCT07228221 — Standalone iStent Infinite and iDose TR for Management of Moderate to Severe Open Angle Glaucoma · Phase 4 · recruiting
NCT06883123 — Efficacy of Simbrinza and Rocklatan vs Cosopt and Latanoprost · Phase 4 · recruiting
NCT06666855 — A Phase III Study in Subjects With Primary Open Angle Glaucoma or Ocular Hypertension in China · Phase 3 · active not recruiting
NCT06246136 — Comparative Effectiveness and Safety of ELIOS in Patients With Open-Angle Glaucoma Undergoing Cataract Surgery · NA · recruiting
NCT06061718 — Travoprost Intraocular Implant in Conjunction With Cataract Surgery · Phase 3 · active not recruiting

Other New World Medical, Inc. trials

Trials by the same sponsor.

NCT06230393 — An Extension Trial for Patients With Open-Angle Glaucoma Who Participated in the DF6-CL-20-01 Protocol. · terminated
NCT05089474 — A First in Human Clinical Trial to Evaluate the Safety and Effectiveness of the STREAMLINE SURGICAL SYSTEM in Patients W · NA · completed
NCT04700189 — A FIH Trial of the STREAMLINE™ SURGICAL SYSTEM · NA · completed
NCT05131087 — A First-In-Human Clinical Trial to Evaluate the Safety, Effectiveness and Surgical Characteristics of CADENCE in Patient · NA · completed

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT05280366 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by New World Medical, Inc.
Last refreshed: 12 November 2024

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05280366.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing