Last reviewed 2026-04-19 · How we verify

Open-angle glaucoma

Approved treatments

• Didroxan
• Alphagan · Senju Pharmaceutical Co., Ltd
• Catapres-Tts-1 · Lavipharm
• Trusopt · Merck & Co.
  Trusopt works by inhibiting the enzyme carbonic anhydrase 2, which is involved in the production of aqueous humor in the eye.
• Miostat · Novartis
  Miostat works by mimicking the action of the neurotransmitter acetylcholine to increase the outflow of aqueous humor and reduce intraocular pressure.
• Betagan · AbbVie
• Alphagan · Senju Pharmaceutical Co., Ltd
• Betaxon · Alcon Pharms Ltd
• Aceclidin
  VIZZ, a pupil-selective miotic, contracts the iris sphincter muscle to improve vision by extending depth of focus.
• Taxol · Pfizer
  Taxol works by binding to tubulin and preventing the formation of microtubules, which are essential for cell division.
• Iopidine · Harrow Health
• Clonidin · Medical University of Vienna
• Azopt · Alcon Research
• Bentos
  Bentos works by reducing the production of fluid in the eye, thereby lowering intraocular pressure.
• Cogmine
• Optipranolol · Bausch Health
• Azopt · Novartis
  Brinzolamide reduces intraocular pressure by inhibiting carbonic anhydrase II, decreasing aqueous humor secretion.
• Xalatan · Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
• Epipen · Pfizer Inc.
  Epipen works by stimulating the alpha-1D adrenergic receptor to rapidly increase heart rate, blood pressure, and bronchodilation.
• Xalatan · Thea Pharma
  Xalatan works by increasing the outflow of fluid from the eye, reducing pressure.
• Travatan
  Travatan works by increasing the outflow of fluid from the eye to reduce pressure.
• Keveyis
  Keveyis works by inhibiting the enzyme carbonic anhydrase, which is involved in the production of aqueous humor in the eye.
• Lumigan
  Lumigan works by increasing the outflow of fluid from the eye to reduce pressure.
• Neptazane · Pfizer
• Taxol · Pfizer
• Diamox · Teva
• Bupivacaine Hydrochloride And Epinephrine · Pfizer Inc.
  Epinephrine works by stimulating the alpha-1D adrenergic receptor to increase heart rate and blood pressure, and to constrict blood vessels.
• Ocupress
• Dipivefrin · AbbVie
• Salagen
• Vyzulta · Bausch Health
  Vyzulta works by activating the Prostaglandin F2-alpha receptor, which increases the outflow of aqueous humor from the eye, thereby reducing intraocular pressure.
• Rhopressa · Alcon Labs Inc
  Netarsudil reduces intraocular pressure by increasing aqueous humor outflow through the trabecular meshwork.
• Betoptic · Novartis
  Betaxolol works by blocking the beta-1 adrenergic receptor in the heart and eyes, reducing heart rate and pressure, and decreasing intraocular pressure.
• Phospholine Iodide · Fera Pharms Llc
• Taxol · Pfizer
• Epinephrin · United States Naval Medical Center, San Diego
• Travatan · Alcon Research
• Abraxane · The First Affiliated Hospital with Nanjing Medical University
• Salagen · Alberta Health services
• Taxol · M.D. Anderson Cancer Center

Competitive intelligence

For the full treatment-landscape CI brief — marketed leaders side-by-side, pipeline by phase, recent regulatory actions, sponsor landscape:

• Open-angle glaucoma patent landscape — cliff calendar, originator estates, attackable patents
• Open-angle glaucoma treatment landscape brief
• Open-angle glaucoma treatment updates RSS

Frequently asked questions about Open-angle glaucoma

Related

• Treatment landscape: Open-angle glaucoma patent cliff · Open-angle glaucoma CI report
• Treatment: Didroxan
• Treatment: Alphagan · Senju Pharmaceutical Co., Ltd
• Treatment: Catapres-Tts-1 · Lavipharm
• Treatment: Trusopt · Merck & Co.
• Treatment: Miostat · Novartis
• All diseases: Browse the disease index · Disease landscape hub

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing