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NCT05271357: RESTORE
Transcranial Magnetic Stimulation for Depression in Autism Spectrum Conditions
NA trial testing Bilateral TMS in Autism Spectrum Disorder in 17 participants. Completed in 23 February 2023.
23 February 2023
Quick facts
| Lead sponsor | Children's Hospital Medical Center, Cincinnati |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 17 |
| Start date | 24 November 2021 |
| Primary completion | 23 February 2023 |
| Estimated completion | 23 February 2023 |
| Sites | 1 location across United States |
Drugs / interventions tested
- Bilateral TMS
- Unilateral TMS
Conditions studied
- Autism Spectrum Disorder — all drugs for Autism Spectrum Disorder →
- Major Depressive Disorder — all drugs for Major Depressive Disorder →
Sponsor
Children's Hospital Medical Center, Cincinnati
Who can join
Adults 12 to 26, any sex, with Autism Spectrum Disorder or Major Depressive Disorder. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
In this research study the investigators aim to learn more about the therapeutic effects of a newer form of non-invasive transcranial magnetic stimulation (TMS), called theta burst simulation (TBS), on refractory depression in Autism Spectrum Conditions.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
ACNP 61<sup>st</sup> Annual Meeting: Poster Abstracts P271-P540.
· 2022 · cited 7× · PMID 36456694 · DOI 10.1038/s41386-022-01485-0
Verify or expand the search:
- PubMed search for NCT05271357
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05271357 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Children's Hospital Medical Center, Cincinnati
- Last refreshed: 7 February 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05271357.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing