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NCT05271019
Efficacy of Early Inspiratory Muscle Training in Lung Transplanted Patients
NA trial testing Threshold load device in Lung Transplant Recipients in 54 participants. Currently enrolling.
15 December 2024
Quick facts
| Lead sponsor | Puerta de Hierro University Hospital |
|---|---|
| Phase | NA |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | double |
| Primary purpose | treatment |
| Enrollment | 54 |
| Start date | 4 February 2022 |
| Primary completion | 15 December 2024 |
| Estimated completion | 30 April 2025 |
| Sites | 1 location across Spain |
Drugs / interventions tested
- Threshold load device
Conditions studied
- Lung Transplant Recipients — all drugs for Lung Transplant Recipients →
- Muscle Weakness — all drugs for Muscle Weakness →
- Respiratory Insufficiency — all drugs for Respiratory Insufficiency →
- Pulmonary Rehabilitation — all drugs for Pulmonary Rehabilitation →
Sponsor
Puerta de Hierro University Hospital
Who can join
Adults 18 to 80, any sex, with Lung Transplant Recipients or Muscle Weakness. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Lung transplantation is an effective therapeutic option in the end-stage of chronic respiratory diseases. Lung transplantation improves lung function in terms of capacity and volume. However, the transplanted patient still suffers from muscle weakness and exercise intolerance. In recent years, respiratory physiotherapy work has intensified in critically ill patients with respiratory muscle weakness and the application of inspiratory muscle training (IMT), which has been shown in several studies to increase inspiratory muscle strength (IMT), improve ventilation and reduce the sensation of shortness of breath. Despite this emerging evidence, inspiratory muscle training (IMT) is not standard practice in most ICUs around the world, nor is it included in a protocolised manner among the components of a pulmonary rehabilitation programme. Given the limited evidence, the investigators propose to conduct this randomised controlled clinical trial in lung transplant recipients. The study will compare two groups of transplanted patients, a control group that will follow the rehabilitation programme and standard medical care and another experimental group that will also perform inspiratory muscle training. This study aims to analyse the effect of IMT on inspiratory muscle strength, exercise capacity and quality of life in lung transplant patients.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT05271019
- Europe PMC full search
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Related trials
Other recruiting trials for Lung Transplant Recipients
Currently open trials in the same condition.
- NCT07035743 — Bronchial Response to Exercise After Double Lung Transplantation · recruiting
Other Puerta de Hierro University Hospital trials
Trials by the same sponsor.
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- NCT07008729 — Heart Failure Patient Management and Interventions Using Continuous Patient Monitoring Outside Hospitals and Real-world · NA · active not recruiting
- NCT06285760 — Effect of Acetazolamide on Diuresis and Natriuresis in Patients With Acute Heart Failure (SANDI STUDY) · recruiting
- NCT06293495 — Incidence of Cut-out Using Intramedullary Nails With Double Cephalic Screw vs. Unique in Pertrochanteric Fractures · NA · unknown
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05271019 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Puerta de Hierro University Hospital
- Last refreshed: 2 April 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05271019.
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