NCT05267847 is a NA clinical trial of Cryotherapy in Pain, Procedural, sponsored by Minia University.

Who is sponsoring NCT05267847?

NCT05267847 is sponsored by Minia University.

What drugs are being tested in NCT05267847?

Interventions in NCT05267847: Cryotherapy, Traditional local anesthesia.

What condition does NCT05267847 study?

NCT05267847 studies Pain, Procedural.

Is NCT05267847 still recruiting?

NCT05267847 is currently status unknown. Last updated 4 March 2022.

Last reviewed 2022-03-04 · How we verify

NCT05267847

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

The Success Rate of Cryotherapy Application in Primary Molars With Signs of Irreversible Pulpitis

Status unknown NA Last updated 4 March 2022

What this trial tests

NA trial testing Cryotherapy in Pain, Procedural in 188 participants. Status unknown.

Timeline

22 February 2022

Primary endpoint
30 April 2022

30 April 2022

Quick facts

Lead sponsor	Minia University
Phase	NA
Status	Status unknown
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	single
Primary purpose	supportive care
Enrollment	188
Start date	22 February 2022
Primary completion	30 April 2022
Estimated completion	30 April 2022
Sites	1 location across Egypt

Drugs / interventions tested

Cryotherapy (CRYOTHERAPY) — full drug profile →
Traditional local anesthesia

Conditions studied

Pain, Procedural — all drugs for Pain, Procedural →

Sponsor

Minia University

Who can join

Adults 5 to 9, any sex, with Pain, Procedural. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The study is designed as a randomized controlled trial with two parallel groups. Children aged 5-9 years with primary molars from suffered symptomatic signs of irreversible pulpitis will be randomly assigned into two groups. The first group (experimental group) will be injected with 4% articaine 1:100.000 epinephrine (inferior alveolar nerve block). For the second group, the mandibular second primary molars will be anesthetized using 4% articaine 1:100.000 epinephrine using inferior alveolar nerve block.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Cryotherapy and pain intensity during endodontic treatment of mandibular first permanent molars with symptomatic irreversible pulpitis: A randomized controlled trial.
Elheeny AAH, Sermani DI, Saliab EA, Turky M. · · 2023 · cited 6× · PMID 37268843 · DOI 10.1007/s00784-023-05084-1

Verify or expand the search:

Other trials of Cryotherapy

Trials testing the same drug.

NCT07384078 — High Intensity Focused Ultrasound vs. Cryotherapy in the Treatment of Basal Cell Carcinomas and Bowen's Disease in Adult · NA · not yet recruiting
NCT07245004 — Effect of Cryotherapy on Postoperative Pain for Pulpotomy · EARLY_PHASE1 · active not recruiting
NCT07517367 — Intraoral Cryotherapy on Anesthetic Efficacy in Mandibular Incisors · Phase 4 · recruiting
NCT07366736 — Monocentric Randomised Controlled Trial Assessing Cryocompression Following Total Knee Replacement · NA · recruiting
NCT07211412 — Acute Cryotherapy on Musculoskeletal Function and Biomarkers · NA · not yet recruiting

Other recruiting trials for Pain, Procedural

Currently open trials in the same condition.

NCT07313735 — The Effect of Cartoon Character-Printed Band Use During Burn Dressing on Fear, Stress, Pain, and Physiological Parameter · NA · recruiting
NCT07314450 — Procedural Sedation and Analgesia for Treatment of Adults With Fractures and Dislocations in the Emergency Department · recruiting
NCT06520150 — Evaluation of the Effectiveness of Two Methods of Regional Anesthesia During S-ICD Implantation Procedure. · NA · recruiting
NCT06284473 — Ketamine as a Supplement to Local Anesthesia for Minor Procedures · Phase 4 · recruiting

Other Minia University trials

Trials by the same sponsor.

NCT07525687 — Temporary Uterine Tourniquet Application Versus Local Myometrial Epinephrine Injection During Laparoscopic Myomectomy · NA · not yet recruiting
NCT07525674 — Vacuum Sealing Drainage (VSD) in Promoting Wound Healing and Reducing Complications in Post-Infected Obstetric and Gynec · NA · not yet recruiting
NCT07529587 — Laparoscopic Umbilico-uterine Trunk Clipping Approach in the Management of Enhanced Myometrial Vascularity · NA · not yet recruiting
NCT07500558 — Ultrasound Guided Infratemporal Sphenopalatine Ganglion Supravoltage Versus Standard Voltage Pulsed Radiofrequency for P · NA · not yet recruiting
NCT07428057 — Postoperative Hypocalcemia After Thyroidectomy · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT05267847 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Minia University
Last refreshed: 4 March 2022

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05267847.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing