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NCT07517367

Intraoral Cryotherapy on Anesthetic Efficacy in Mandibular Incisors

Recruiting now Phase 4 Last updated 8 April 2026
What this trial tests

Phase 4 trial testing Cryotherapy in Symptomatic Irreversible Pulpitis (SIP) in 98 participants. Currently enrolling.

Timeline
31 December 2025
Primary endpoint
1 August 2026
30 August 2026

Quick facts

Lead sponsorOndokuz Mayıs University
PhasePhase 4
StatusRecruiting now
Study typeINTERVENTIONAL
Allocationrandomized
Designparallel
Maskingdouble
Primary purposetreatment
Enrollment98
Start date31 December 2025
Primary completion1 August 2026
Estimated completion30 August 2026
Sites1 location across Turkey (Türkiye)

Drugs / interventions tested

Conditions studied

Sponsor

Ondokuz Mayıs University

Who can join

Adults 18 to 60, any sex, with Symptomatic Irreversible Pulpitis (SIP). Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The aim is to compare the contributions of intraoral cryotherapy and supplemental lingual infiltration anesthesia to buccal infiltration anesthesia in mandibular incisor teeth with irreversible pulpitis in terms of anesthetic efficacy, and to evaluate the effect of adding intraoral cryotherapy to buccal anesthesia on anesthetic efficacy.

Publications & conference data

No peer-reviewed publications indexed yet for this trial.

Verify or expand the search:

Other trials of Cryotherapy

Trials testing the same drug.

Other recruiting trials for Symptomatic Irreversible Pulpitis (SIP)

Currently open trials in the same condition.

Other Ondokuz Mayıs University trials

Trials by the same sponsor.

Verify against primary sources

Data sources for this page

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07517367.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing