Who is sponsoring NCT05264467?

NCT05264467 is sponsored by Universidad de Concepcion.

What drugs are being tested in NCT05264467?

Interventions in NCT05264467: Platelet rich fibrin on colorectal anastomosis.

What condition does NCT05264467 study?

NCT05264467 studies Anastomotic Leak, Platelet-Rich Fibrin, Colorectal Surgery.

Is NCT05264467 still recruiting?

NCT05264467 is currently completed. Last updated 3 March 2022.

Last reviewed 2022-03-03 · How we verify

NCT05264467

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Leukocyte and and Platelet-rich Fibrin Plasma for the Prevention of Anastomotic Leakage in Colorectal Anastomosis

Completed Phase 2, PHASE3 Last updated 3 March 2022

What this trial tests

Phase 2, PHASE3 trial testing Platelet rich fibrin on colorectal anastomosis in Anastomotic Leak in 106 participants. Completed in 10 August 2021.

Timeline

12 March 2018

Primary endpoint
9 July 2021

10 August 2021

Quick facts

Lead sponsor	Universidad de Concepcion
Phase	Phase 2, PHASE3
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	none
Primary purpose	prevention
Enrollment	106
Start date	12 March 2018
Primary completion	9 July 2021
Estimated completion	10 August 2021
Sites	1 location across Chile

Drugs / interventions tested

Platelet rich fibrin on colorectal anastomosis — full drug profile →

Conditions studied

Anastomotic Leak — all drugs for Anastomotic Leak →
Platelet-Rich Fibrin — all drugs for Platelet-Rich Fibrin →
Colorectal Surgery — all drugs for Colorectal Surgery →

Sponsor

Universidad de Concepcion — full company profile →

Who can join

15 and older, any sex, with Anastomotic Leak or Platelet-Rich Fibrin. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Anastomotic leak rate in colorectal surgery is estimated between 4 and 20 percent. Leukocyte and and platelet-rich fibrin plasma (L-PRF) is second generation platelet concentrate whose application in colorectal anastomosis in animals has shown promising results that suppose a lower leakage rate. The objective of this study was to assess the feasibility of using L-PRF in colorectal surgery and to determine the incidence of anastomotic leakage after colorectal anastomosis.

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.

Verify or expand the search:

Other recruiting trials for Anastomotic Leak

Currently open trials in the same condition.

NCT07449208 — Registry Study of People Who Are Having an Esophagectomy and Are at High Risk of Anastomotic Leak · recruiting
NCT07351071 — Post-Market Study of the Signia Circular Stapler With Tri-Staple Technology in Left-sided Colon, Sigmoid, and Rectal Res · NA · recruiting
NCT07144683 — Anastomotic Leakage After Colorectal Surgery. · recruiting
NCT07036588 — PARLAR-02 Trial：Modified Transanal Drainage Tube Use for Preventing Anastomotic Leakage · NA · recruiting
NCT06553261 — Anastomotic Leakage in Right Colectomy · recruiting

Other Universidad de Concepcion trials

Trials by the same sponsor.

NCT06580990 — Neck-specific Exercises Effectively Improves Whiplash-associated Disorders. · NA · recruiting
NCT06423404 — Active Breaks on Mental Health and Classroom Climate in Chilean Schoolchildren Aged 6 to 10 · NA · enrolling by invitation
NCT05609760 — Pictograms to Facilitate Comprehension of Medical Indications · NA · terminated
NCT07087704 — Effects of a Chilean Diet Supplemented With Gevuina Avellana on Lipid Profile in Humans With Hypercholesterolemia · NA · completed
NCT06423209 — Efficacy of a Training Program in Adults Following a Vegan Diet Versus an Omnivorous Diet · NA · completed

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT05264467 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Universidad de Concepcion
Last refreshed: 3 March 2022

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05264467.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing