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NCT07351071: SECURE
Post-Market Study of the Signia Circular Stapler With Tri-Staple Technology in Left-sided Colon, Sigmoid, and Rectal Resections
NA trial testing Signia™ circular stapler with Tri-Staple™ Technology (Signia™ Circular Stapling system) in Colorectal Anastomosis in 137 participants. Currently enrolling.
31 December 2026
Quick facts
| Lead sponsor | Medtronic - MITG |
|---|---|
| Phase | NA |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 137 |
| Start date | 30 December 2025 |
| Primary completion | 31 December 2026 |
| Estimated completion | 28 February 2027 |
| Sites | 8 locations across United States |
Drugs / interventions tested
- Signia™ circular stapler with Tri-Staple™ Technology (Signia™ Circular Stapling system)
Conditions studied
- Colorectal Anastomosis — all drugs for Colorectal Anastomosis →
- Left-sided Colon Resection — all drugs for Left-sided Colon Resection →
- Anastomotic Leak — all drugs for Anastomotic Leak →
- Anastomotic Complication — all drugs for Anastomotic Complication →
Sponsor
Medtronic - MITG — full company profile →
Who can join
18 and older, any sex, with Colorectal Anastomosis or Left-sided Colon Resection. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The purpose of this study is to evaluate the safety and performance of the Signia™ power handle, Signia™ circular adapter, and Signia™ Tri-Staple™ 2.0 circular reloads (hereafter referred to as Signia™ circular stapler) in patients undergoing left sided colon, sigmoid, or rectal resections in a post market setting.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT07351071
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Colorectal Anastomosis
Currently open trials in the same condition.
- NCT07417358 — Single-Stapled Technique for Colorectal Anastomosis · recruiting
- NCT06578065 — Colorectal Anastomosis Outcomes Using the Novel Powered Circular Stapler Compared With Manual Circular Staplers. · NA · recruiting
- NCT06546176 — End to End Anastomosis With Omega Suture Versus End to Anterior Rectal Wall In Colorectal Anastomosis in Sigmoid and Upp · NA · recruiting
Other Medtronic - MITG trials
Trials by the same sponsor.
- NCT07166341 — Accuracy Verification of the INVOS PM7100 · active not recruiting
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- NCT06710795 — AFFIX: Post-market Study of MaxTack™ Motorized Fixation Device in Subjects Undergoing Ventral Hernia Repair · NA · active not recruiting
- NCT06638073 — Continuous Connected Patient Care (CCPC), a Pilot Testing a Novel Device for Continuous Vitals Monitoring - Department o · recruiting
- NCT06638060 — Continuous Connected Patient Care (CCPC), a Pilot Testing a Novel Device for Continuous Vitals Monitoring - Older Adults · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07351071 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Medtronic - MITG
- Last refreshed: 17 March 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07351071.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing