NCT05248815 is a clinical trial in Arthropathy of Knee, sponsored by Vastra Gotaland Region.

Who is sponsoring NCT05248815?

NCT05248815 is sponsored by Vastra Gotaland Region.

What condition does NCT05248815 study?

NCT05248815 studies Arthropathy of Knee, Osteo Arthritis Knee.

Is NCT05248815 still recruiting?

NCT05248815 is currently completed. Last updated 25 May 2025.

Last reviewed 2025-05-25 · How we verify

NCT05248815

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Muscle Strength and Total Knee Replacement

Completed Last updated 25 May 2025

What this trial tests

trial in Arthropathy of Knee in 57 participants. Completed in 1 December 2023.

Timeline

12 November 2021

Primary endpoint
1 December 2023

1 December 2023

Quick facts

Lead sponsor	Vastra Gotaland Region
Status	Completed
Study type	OBSERVATIONAL
Enrollment	57
Start date	12 November 2021
Primary completion	1 December 2023
Estimated completion	1 December 2023
Sites	3 locations across Sweden

Conditions studied

Arthropathy of Knee — all drugs for Arthropathy of Knee →
Osteo Arthritis Knee — all drugs for Osteo Arthritis Knee →

Sponsor

Vastra Gotaland Region — full company profile →

Who can join

65 and older, any sex, with Arthropathy of Knee or Osteo Arthritis Knee. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Purposes: To compare knee extensor muscle strength, physical function and self-reported function before and after total knee replacement with healthy age-matched controls. To describe changes in knee extensor muscle strength up to one year after surgery. To study the relationship between changes in knee extensor muscle strength and changes in physical function, self-reported function and physical activity level and the relationship between changes in knee extensor muscle strength and satisfaction. Methods: A prospective observational study and comparison with controls. 50-55 individuals aged 65 or older, scheduled for total knee arthroplasty will be recruited to the study group. Measurement of study group 0-2 weeks before surgery and 3, 6 and 12 months following surgery. Comparison with 50-55 healthy age-matched controls.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Knee extensor muscle strength, physical function and patient-reported outcomes the first year after total knee arthroplasty: a prospective longitudinal study.
Sjöström P, Nordeman L, Rolfson O, Larsson A. · · 2025 · PMID 41121108 · DOI 10.1186/s12891-025-09257-9

Verify or expand the search:

Other recruiting trials for Arthropathy of Knee

Currently open trials in the same condition.

NCT07180953 — Impact of Dexamethasone Route on Pain and Inflammation in iPACK With ACB for Knee Arthroplasty · Phase 4 · recruiting
NCT05290818 — Total Versus Robotic Assisted Unicompartmental Knee Replacement · NA · recruiting
NCT06832995 — Incidence and Risk Factors for Post-Anesthetic Morphine Titration in Recovery Room After Hip and Knee Arthroplasties · active not recruiting
NCT03869996 — Total Knee Arthroplasty: Fast Track Protocol is the Future? · NA · recruiting
NCT03674697 — The Effect of Light Therapy on Post-Surgical Pain · NA · active not recruiting

Other Vastra Gotaland Region trials

Trials by the same sponsor.

NCT07430865 — The RECOVER Study - Postpartum Recovery of Pelvic Floor Structures and the Impact of Early Rehabilitation · NA · recruiting
NCT07472335 — Home-based Acute Care for Older Persons Initiated by the Emergency Medical and Ambulance Services - a Retrospective Obse · not yet recruiting
NCT07246577 — The VGR GCA Cohort: Ultrasound, Biopsy and Biomarkers - Novel Methods for Diagnosis, Monitoring and Prognosis in Giant C · recruiting
NCT07449338 — Prospective Cohort Study of Response and Tolerability of Accelerated Intermittent Theta-burst Stimulation (1W-AiTBS) · not yet recruiting
NCT07334340 — Modified vs Standard CDED: Evaluation of a Nordic Adaptation of Nutritional Therapy in Paediatric Crohn's Disease · NA · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT05248815 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Vastra Gotaland Region
Last refreshed: 25 May 2025

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05248815.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing